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生命的起源:一个历史、化学与进化的问题。

The origin of life: a problem of history, chemistry, and evolution.

作者信息

Ma Wentao

机构信息

College of Life Sciences, Wuhan University, Wuhan 430072, P. R. China.

出版信息

Chem Biodivers. 2014 Dec;11(12):1998-2010. doi: 10.1002/cbdv.201400188.

Abstract

The origin of life is a field full of controversies, not only because of our vague understanding concerning the relevant issues, but also, perhaps more often, owing to our dim conceptual framework throughout the whole field. To improve this situation, an in-depth conceptual dissection is presented here. It is elucidated that, at its core, the origin of life has three aspects. The facts involved in the process are taken as the historical aspect, which is destined to be uncertain and often irrelevant to debate regarding details. The rules involved include two distinct aspects: chemical mechanisms operated in the whole process, while evolutionary mechanisms joined in only after the emergence of the first Darwinian entities - and then accounted for the subsequent buildup of complexity (this cannot be explained solely by natural selection). Basically, we can ask about the possibility of any assumed event in the origin of life: 'Is it evolutionarily plausible, chemically feasible, and historically likely?' Clues from any of the three aspects may be quite valuable in directing our explorations on the other two. This conceptual dissection provides a clearer context for the field, which may even be more useful than any sort of specific research.

摘要

生命起源是一个充满争议的领域,这不仅是因为我们对相关问题的理解模糊,还可能更主要的是由于我们在整个领域的概念框架都很模糊。为了改善这种情况,本文进行了深入的概念剖析。结果表明,生命起源的核心有三个方面。该过程中涉及的事实被视为历史方面,这注定是不确定的,并且通常与关于细节的争论无关。所涉及的规则包括两个不同的方面:整个过程中起作用的化学机制,而进化机制仅在第一个达尔文式实体出现后才加入——然后解释了随后复杂性的增加(这不能仅由自然选择来解释)。基本上,我们可以询问生命起源中任何假定事件的可能性:“它在进化上是否合理,在化学上是否可行,在历史上是否可能?”来自这三个方面中任何一个方面的线索在指导我们对其他两个方面的探索时可能都非常有价值。这种概念剖析为该领域提供了更清晰的背景,这甚至可能比任何特定类型的研究都更有用。

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