通过高分辨率质谱法和计算机模拟方法研究金手指形成。
Gold finger formation studied by high-resolution mass spectrometry and in silico methods.
作者信息
Laskay Ü A, Garino C, Tsybin Y O, Salassa L, Casini A
机构信息
Biomolecular Mass Spectrometry Laboratory, Ecole Polytechnique Fédérale de Lausanne (EPFL), 1015 Lausanne, Switzerland.
出版信息
Chem Commun (Camb). 2015 Jan 31;51(9):1612-5. doi: 10.1039/c4cc07490d.
High-resolution mass spectrometry and quantum mechanics/molecular mechanics studies were employed for characterizing the formation of two gold finger (GF) domains from the reaction of zinc fingers (ZF) with gold complexes. The influence of both the gold oxidation state and the ZF coordination sphere in GF formation provided useful insights into the possible design of new gold complexes targeting specific ZF motifs.
采用高分辨率质谱和量子力学/分子力学研究方法来表征锌指（ZF）与金配合物反应形成两个金指（GF）结构域的过程。金的氧化态和ZF配位环境对GF形成的影响为设计靶向特定ZF基序的新型金配合物提供了有益的见解。
Zotero 插件