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1-芳基-5-(邻甲氧基苯基)-2-S-苄基异硫脲的合成抗菌及抗癌活性评价

Synthesis Antimicrobial and Anticancer Evaluation of 1-Aryl-5-(o-methoxyphenyl)-2-S-benzyl Isothiobiurets.

作者信息

Ansari Mohammed M, Deshmukh Shirish P, Khan Rizwan, Musaddiq Mohammed

机构信息

P.G. Department of Chemistry, Shri Shivaji College, Akola, Maharashtra 444001, India.

P.G. Department of Microbiology, Shri Shivaji College, Akola, Maharashtra 444001, India.

出版信息

Int J Med Chem. 2014;2014:352626. doi: 10.1155/2014/352626. Epub 2014 Nov 20.

Abstract

A series of S-benzyl aryl thiourea were condensed with o-Methoxy phenyl isocyanate to yield respective isothiobiuret derivatives. The newly synthesized compounds were characterized by (1)H-NMR, IR, and Mass Spectral studies and tested for biological activities.

摘要

一系列S-苄基芳基硫脲与邻甲氧基苯基异氰酸酯缩合,生成相应的异硫代双缩脲衍生物。通过¹H-NMR、红外光谱和质谱研究对新合成的化合物进行了表征,并对其生物活性进行了测试。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba87/4258328/ba9e6e773d5c/IJMC2014-352626.sch.001.jpg

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