Özkan Burak, Coskuner Enis Rauf, Turk Ali, Akkus Emre, Yalçın Veli
Department of Urology, Acibadem Bakirkoy Hospital, Faculty of Medicine, Istanbul, Acibadem University, Turkey.
Department of Urology, Acibadem Bakirkoy Hospital, Faculty of Medicine, Istanbul, Acibadem University, Turkey.
Urology. 2015 Jan;85(1):113-7. doi: 10.1016/j.urology.2014.09.030.
To investigate the treatment outcomes among patients diagnosed with penile Mondor disease and to evaluate the effect of the disease on erectile function.
A total of 30 patients diagnosed with penile Mondor disease were enrolled in the study. All patients underwent physical examination and penile Doppler ultrasonography and filled in the International Index of Erectile Function (IIEF-5) questionnaire at regular intervals. Pharmacotherapy was started when penile Mondor disease was diagnosed. After the data were confirmed to be normally distributed using Kolmogorov-Smirnov test, the differences between the 3 IIEF-5 scores were evaluated using repeated measures analysis of variance and post hoc Bonferroni tests.
The mean age of the patients was 34.3 years (range, 25-48 years). Ten patients had prolonged sexual intercourse, 4 had recent intestinal infection history, 2 had recent long-haul flights, 1 had sickle cell anemia, and 2 had penile trauma caused by sexual intercourse. Nine patients were considered idiopathic. Mean IIEF-5 scores at the baseline and at 1- and 2-month follow-ups were 20.87, 20.07, and 20.93, respectively. Although no significant difference was found between the baseline and the 2-month follow-up IIEF-5 scores, significant differences between the baseline and the 1-month (P = .004) and the 1- and 2-month follow-up IIEF-5 scores (P = .0001) were detected.
Penile Mondor disease is a rare complication that can be successfully treated with medical therapy and conservative approach. Our series showed that penile Mondor's disease does not lead to permanent deformation of the penis or erectile dysfunction.
探讨阴茎蒙多氏病患者的治疗效果,并评估该疾病对勃起功能的影响。
本研究共纳入30例诊断为阴茎蒙多氏病的患者。所有患者均接受体格检查和阴茎多普勒超声检查,并定期填写国际勃起功能指数(IIEF-5)问卷。确诊阴茎蒙多氏病后即开始药物治疗。经柯尔莫哥洛夫-斯米尔诺夫检验确认数据呈正态分布后,采用重复测量方差分析和事后邦费罗尼检验评估3个IIEF-5评分之间的差异。
患者的平均年龄为34.3岁(范围25 - 48岁)。10例患者有性交时间延长情况,4例近期有肠道感染史,2例近期有长途飞行经历,1例患有镰状细胞贫血,2例因性交导致阴茎外伤。9例患者病因不明。基线时及1个月和2个月随访时的平均IIEF-5评分分别为20.87、20.07和20.93。虽然基线与2个月随访时的IIEF-5评分无显著差异,但基线与1个月(P = .004)以及1个月和2个月随访时的IIEF-5评分之间存在显著差异(P = .0001)。
阴茎蒙多氏病是一种罕见的并发症,可通过药物治疗和保守方法成功治愈。我们的系列研究表明,阴茎蒙多氏病不会导致阴茎永久性变形或勃起功能障碍。