Hernigou Philippe, Flouzat Lachaniette Charles, Delambre Jerome, Guissou Isaac, Dahmani Omar, Ibrahim Ouali Mohamed, Poignard Alexandre
Hôpital Henri Mondor, Orthopaedic Surgery, Créteil, France,
Int Orthop. 2015 Jul;39(7):1295-300. doi: 10.1007/s00264-014-2633-2. Epub 2014 Dec 24.
The efficacy of immediate full weight bearing in accelerating bone regeneration after medial opening wedge high tibial osteotomy (HTO) was evaluated in patients operated with the Limmed system (locked plate fixation) that allows dynamisation of the site of the osteotomy.
A case series of 50 consecutive osteotomies performed with Limmed locked plate fixation for medial opening wedge HTO had full weight bearing immediately after the HTO; they were compared to a case-matched control series of 50 HTOs (50 patients) performed using the same implant without locked screws. Radiographs were observed at 30 days and two, three, four, five and six months after surgery. The osteotomy gap was only partially filled by a medial bone substitute leaving the lateral part unfilled. Bone surface areas of osteotomy planes were quantified and opening volumes were determined applying wedge heights. End points for evaluation included radiographic evidence of bone regeneration in the volume created by the opening of the osteotomy.
Statistically significant differences were seen between the groups in terms of radiographic union and radiographic stability between the two groups. Patients of the Limmed group reported a shorter time for union (average four weeks difference) without loss of correction during healing. At the radiographic evaluation, there was a significant increase in osseointegration in the group with weight bearing compared to the control group without weight bearing with increased rate of speed to fill the void volume of the osteotomy. The computed tomography scan of the grafted area at four months after surgery showed no significant difference in the quality of the newly formed bone between the two groups.
The Limmed medial opening wedge HTO system with immediate full weight bearing accelerates bone graft substitute osseointegration and bone healing as compared with controls without full weight bearing.
在使用Limmed系统(锁定钢板固定)进行手术的患者中评估即刻完全负重对内侧开口楔形高位胫骨截骨术(HTO)后加速骨再生的疗效,该系统允许截骨部位动态化。
对50例连续采用Limmed锁定钢板固定进行内侧开口楔形HTO的患者在HTO后立即完全负重;将他们与50例采用相同植入物但无锁定螺钉的病例匹配对照组(50例患者)进行比较。在术后30天以及术后2、3、4、5和6个月观察X线片。截骨间隙仅部分由内侧骨替代物填充,外侧部分未填充。对截骨平面的骨表面积进行量化,并根据楔形高度确定开口体积。评估的终点包括截骨开口所形成体积内骨再生的X线证据。
两组在X线愈合和X线稳定性方面存在统计学显著差异。Limmed组患者报告愈合时间更短(平均相差四周),且愈合过程中无矫正丢失。在X线评估中,与无负重的对照组相比,负重组的骨整合有显著增加,填充截骨空隙体积的速度加快。术后四个月移植区域的计算机断层扫描显示两组新形成骨的质量无显著差异。
与无完全负重的对照组相比,采用Limmed内侧开口楔形HTO系统并即刻完全负重可加速骨移植替代物的骨整合和骨愈合。