凝血的空间特性：二十年关于凝血酶自持续行波的研究。
Spatial aspects of blood coagulation: two decades of research on the self-sustained traveling wave of thrombin.
机构信息
Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia.
Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia; National Research Center for Hematology, Moscow, 125167, Russia.
出版信息
Thromb Res. 2015 Mar;135(3):423-33. doi: 10.1016/j.thromres.2014.12.014. Epub 2014 Dec 19.
In a number of experimental studies, it has been demonstrated that the forefront of blood coagulation can propagate in the manner of a signal relay. These data strongly support the concept that the formation of a blood clot is governed by a self-sustained traveling wave of thrombin. The present review critically appraises the experimental data obtained in recent decades concerning the self-sustained spatial propagation of thrombin. Open questions regarding the experimental detection of the self-sustained propagation of thrombin are discussed.
在一些实验研究中，已经证明凝血的前沿可以以信号接力的方式传播。这些数据有力地支持了这样一个概念，即血栓的形成是由凝血酶的自我维持传播波所控制的。本文批判性地评价了近几十年来关于凝血酶自我维持空间传播的实验数据。讨论了关于实验检测凝血酶自我维持传播的悬而未决的问题。
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