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床头抬高与胃反流、误吸及压疮的早期结局:一项可行性研究

Head-of-bed elevation and early outcomes of gastric reflux, aspiration and pressure ulcers: a feasibility study.

作者信息

Schallom Marilyn, Dykeman Betsy, Metheny Norma, Kirby John, Pierce Janet

机构信息

Marilyn Schallom is a is a clinical nurse specialist/research scientist for the Department of Research for Patient Care Services, Barnes-Jewish Hospital, St Louis, Missouri. Betsy Dykeman is a nurse educator in the surgical intensive care unit at Barnes-Jewish Hospital. Norma Metheny is the Dorothy A. Votsmier Endowed Chair in Nursing at St Louis University School of Nursing, St Louis, Missouri. John Kirby is is an associate professor at Washington University Medical School and medical director of the wound healing program at Barnes-Jewish Hospital. Janet Pierce is the Christine A. Hartley Endowed Professor of Nursing at the University of Kansas School of Nursing, Kansas City.

出版信息

Am J Crit Care. 2015 Jan;24(1):57-66. doi: 10.4037/ajcc2015781.

Abstract

BACKGROUND

Guidelines recommending head of bed (HOB) elevation greater than 30º to prevent ventilator-associated pneumonia conflict with guidelines to prevent pressure ulcers, which recommend HOB elevation less than 30º.

OBJECTIVES

To examine the feasibility of 45º HOB elevation and describe and compare the occurrence of reflux, aspiration, and pressure ulcer development at 30º and 45º HOB elevation.

METHODS

A randomized 2-day crossover trial was conducted. HOB angle was measured every 30 seconds. Oral and tracheal secretions were analyzed for pepsin presence. Skin was assessed for pressure ulcers. Wilcoxon signed rank tests and Kendall τ correlations were conducted.

RESULTS

Fifteen patients were enrolled; 11 completed both days. Patients were maintained at 30º (mean, 30º) for 96% of minutes and at 45º (mean, 39º) for 77% of minutes. No patients showed signs of pressure ulcers. A total of 188 oral secretions were obtained, 82 (44%) were pepsin-positive; 174 tracheal secretions were obtained, 108 (62%) were pepsin-positive. The median percentage of pepsin-positive oral secretions was not significantly higher (P = .11) at 30º elevation (54%) than at 45º elevation (20%). The median percentage of pepsin-positive tracheal secretions was not significantly higher (P = .37) at 30º elevation (71%) than 45º elevation (67%). Deeper sedation correlated with increased reflux (P = .03).

CONCLUSIONS

HOB elevation greater than 30º is feasible and preferred to 30º for reducing oral secretion volume, reflux, and aspiration without pressure ulcer development in gastric-fed patients receiving mechanical ventilation. More deeply sedated patients may benefit from higher HOB elevations.

摘要

背景

推荐床头抬高大于30°以预防呼吸机相关性肺炎的指南与预防压疮的指南相冲突,后者推荐床头抬高小于30°。

目的

研究床头抬高45°的可行性,并描述和比较床头抬高30°和45°时反流、误吸及压疮发生情况。

方法

进行一项为期2天的随机交叉试验。每30秒测量一次床头角度。分析口腔和气管分泌物中胃蛋白酶的存在情况。评估皮肤有无压疮。进行Wilcoxon符号秩检验和Kendall τ相关性分析。

结果

纳入15例患者;11例完成了两天的试验。患者在30°(平均30°)时保持96%的时间,在45°(平均39°)时保持77%的时间。无患者出现压疮迹象。共获取188份口腔分泌物,82份(44%)胃蛋白酶呈阳性;获取174份气管分泌物,108份(62%)胃蛋白酶呈阳性。床头抬高30°时胃蛋白酶阳性口腔分泌物的中位数百分比(54%)并不显著高于床头抬高45°时(20%)(P = 0.11)。床头抬高30°时胃蛋白酶阳性气管分泌物的中位数百分比(71%)并不显著高于床头抬高45°时(67%)(P = 0.37)。深度镇静与反流增加相关(P = 0.03)。

结论

对于接受机械通气的经胃喂养患者,床头抬高大于30°是可行的,且在减少口腔分泌物量、反流和误吸方面优于30°,同时不会发生压疮。深度镇静程度较高的患者可能从更高的床头抬高角度中获益。

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