Gornik Kara R, Pirie Christopher G, Beamer Gillian L
Department of Clinical Sciences, Cummings School of Veterinary Medicine, Tufts University, North Grafton, MA 01536.
J Am Vet Med Assoc. 2015 Jan 15;246(2):231-5. doi: 10.2460/javma.246.2.231.
A 2-year-old Morgan mare was evaluated because of a corneal ulceration.
An irregular, deep stromal corneal ulcer in an area of malacia was noted in the left eye. Hypopyon was present in the ventral portion of the anterior chamber with moderate aqueous flare. The nictitating membrane of the left eye had hairs originating from its leading edge that contacted the corneal surface.
General anesthesia was induced, and a bulbar pedicle conjunctival graft was performed. The conjunctiva at the leading edge of the nictitating membrane, including the aberrant hair follicles, was excised. Microscopically, a nonkeratinized stratified squamous epithelium, sebaceous glands, and hair shafts were present, confirming a choristoma of pilosebaceous origin at the leading edge of the nictitating membrane. Six weeks after surgery, the horse had no signs of discomfort, with no regrowth of the hairs; no loss of vision was evident.
Ocular choristomas develop secondary to defective fetal cellular differentiation and are rarely reported in the equine literature. The choristoma in this horse contained ectopic hair follicles with hair growth as well as sebaceous glands. This finding emphasizes the importance of a thorough adnexal examination in horses with corneal disease.
一匹2岁的摩根母马因角膜溃疡接受评估。
左眼软化区域存在不规则的深层基质角膜溃疡。前房腹侧有前房积脓,房水闪辉中度。左眼瞬膜前缘有毛发,与角膜表面接触。
诱导全身麻醉,进行球结膜蒂移植术。切除瞬膜前缘的结膜,包括异常毛囊。显微镜检查显示,存在非角化复层鳞状上皮、皮脂腺和毛干,证实瞬膜前缘为毛囊皮脂腺来源的迷芽瘤。术后六周,马无不适迹象,毛发未再生长;视力无明显丧失。
眼迷芽瘤继发于胎儿细胞分化缺陷,在马医学文献中鲜有报道。这匹马的迷芽瘤包含异位毛囊及毛发和皮脂腺。这一发现强调了对患有角膜疾病的马匹进行彻底附属器检查的重要性。