增生型糖尿病视网膜病变患者行全视网膜光凝治疗后眼脉动血流的变化。

Pulsatile ocular blood flow changes after panretinal photocoagulation treatment in patients with proliferative diabetic retinopathy.

机构信息

Department of Ophthalmology, Karadeniz Technical University, Trabzon, Turkey.

出版信息

Turk J Med Sci. 2014;44(3):524-9. doi: 10.3906/sag-1303-87.

Abstract

BACKGROUND/AIM: To prospectively assess the effects of panretinal photocoagulation (PRP) treatment on pulsatile ocular blood flow (POBF) in patients with proliferative diabetic retinopathy (PDRP).

MATERIALS AND METHODS

The study included 40 eyes with PDRP in 27 patients. The PRP treatments were completed in 3 sessions with 3-week intervals. The intraocular pressure (IOP), pulse amplitude (PA), pulse volume (PV), and POBF changes that arose during the sessions were recorded using a blood flow analyzer.

RESULTS

The average age of the patients was 57.37 ± 11.14 years. The pre-PRP basal IOP, PA, PV, and POBF values were 20.44 ± 4.13 mmHg, 4.23 ± 1.73 mmHg, 6.89 ± 2.28 μL, and 21.86 ± 5.83 μL/s, respectively. One month after the completion of the PRP sessions, the values were 18.49 ± 4.44 mmHg, 2.78 ± 1.13 mmHg, 5.27 ± 2.08 μL, and 15.89 ± 5.05 μL/s, respectively, and the differences were significant (P = 0.001, P < 0.0001, P < 0.0001, and P < 0.0001, respectively).

CONCLUSION

PRP treatment reduces the choroidal blood flow and consequently causes significant decreases in IOP, PA, PV, and POBE .

摘要

背景/目的：前瞻性评估全视网膜光凝（PRP）治疗对增生性糖尿病视网膜病变（PDRP）患者脉动眼血流（POBF）的影响。

材料和方法

该研究纳入了 27 例 40 只眼 PDRP 患者。PRP 治疗分 3 个疗程进行，每个疗程间隔 3 周。使用血流分析仪记录治疗期间眼压（IOP）、脉搏幅度（PA）、脉搏容积（PV）和 POBF 的变化。

结果

患者平均年龄为 57.37±11.14 岁。PRP 治疗前基础 IOP、PA、PV 和 POBF 值分别为 20.44±4.13mmHg、4.23±1.73mmHg、6.89±2.28μL 和 21.86±5.83μL/s。PRP 治疗完成 1 个月后，这些值分别为 18.49±4.44mmHg、2.78±1.13mmHg、5.27±2.08μL 和 15.89±5.05μL/s，差异具有统计学意义（P=0.001、P＜0.0001、P＜0.0001 和 P＜0.0001）。