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炎症性腹主动脉瘤的外科治疗:结果与预测因素分析

Surgical treatment of inflammatory abdominal aortic aneurysms: outcome and predictors analysis.

作者信息

Nuellari Edmond, Prifti Edvin, Esposito Giampiero, Kapedani Edmond

机构信息

Division of Cardiovascular Surgery, University Hospital Center of Tirana, Tirana, Albania.

Humanitas Gavazzeni Clinic, Bergamo, Italy.

出版信息

Med Arch. 2014 Aug;68(4):244-8. doi: 10.5455/medarh.2014.68.244-248. Epub 2014 Jul 31.

Abstract

OBJECTIVES

The aim of this study is to report our experience on the postoperative outcome of surgical treatment of inflammatory abdominal aortic aneurysm (IAAA).

MATERIALS AND METHODS

Between 1997-2014, 35 patients with IAAA underwent surgery. The mean age was 63+/-18years. Chronic renal failure was identified in 11(31.4%)patients and confirmed ischemic heart disease in 15(43%)patients. The mean aortic aneurysm diameter was 68+/-25mm. The abdominal aorta was clamped above the renal arteries in 6 (17%) patients.

RESULTS

The hospital mortality was 5.7% (2 patients). Three patients developed an aortic pseudoaneurysm and underwent a redo operation. Another patient developed a femoral anastomotic pseudoaneurysm 7 years after operation and he was treated surgically. The actuarial free-reoperation actuarial survival at 1, 5 and 7 years was 94%, 62% and 50% respectively. The Cox model revealed the delta ESR (p=0.002), ischemic heart disease (p=0.006) and renal failure (p=0.036) as strong predictors for poor overall outcome.

CONCLUSION

Early postoperative outcome in terms of mortality and morbidity seems acceptable, however patients with IAAA have an increased risk for reoperation due to pseudonaneurysm formation. Strong predictors for poor overall outcome seems to be the elevated erythrocyte sedimentation rate, ischemic heart disease and chronic renal failure.

摘要

目的

本研究旨在报告我们关于炎性腹主动脉瘤(IAAA)手术治疗术后结果的经验。

材料与方法

1997年至2014年间,35例IAAA患者接受了手术。平均年龄为63±18岁。11例(31.4%)患者被诊断为慢性肾衰竭,15例(43%)患者被确诊为缺血性心脏病。腹主动脉瘤平均直径为68±25mm。6例(17%)患者在肾动脉上方夹闭腹主动脉。

结果

医院死亡率为5.7%(2例患者)。3例患者发生主动脉假性动脉瘤并接受了再次手术。另1例患者术后7年发生股动脉吻合口假性动脉瘤并接受了手术治疗。1年、5年和7年的无再次手术生存率分别为94%、62%和50%。Cox模型显示,血沉变化值(p=0.002)、缺血性心脏病(p=0.006)和肾衰竭(p=0.036)是总体预后不良的有力预测因素。

结论

就死亡率和发病率而言,术后早期结果似乎可以接受,然而,IAAA患者因假性动脉瘤形成而再次手术的风险增加。血沉升高、缺血性心脏病和慢性肾衰竭似乎是总体预后不良的有力预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea99/4240557/56443229dec2/MA-68-244-g006.jpg

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