Weiss Mia, Gendelman Omer, Twig Gilad, Tobar Ana, Amital Howard
Department of Medicine 'B', Sheba Medical Center, Tel-Hashomer, 52621, Israel.
Rheumatol Int. 2015 Sep;35(9):1597-600. doi: 10.1007/s00296-014-3207-8. Epub 2015 Jan 13.
We describe a patient with rheumatoid arthritis who presented with nephrotic syndrome which was not related neither to drug therapy nor to amyloidosis. Renal biopsy revealed membranous glomerulonephritis. The patient was treated with three cycles of rituximab with complete resolution of the clinical and laboratory evidence of nephrosis. The following report discusses this unusual presentation and clinical response.
我们描述了一名类风湿性关节炎患者,该患者出现了肾病综合征,既与药物治疗无关,也与淀粉样变性无关。肾活检显示为膜性肾小球肾炎。该患者接受了三个周期的利妥昔单抗治疗,肾病的临床和实验室证据完全消失。以下报告讨论了这种不寻常的表现和临床反应。