Li Pei-ling, Tian Yun-jiao, Wang Yan-hua, Zhang Cui-zhen, Gao Jun, Li Yu-hua, Li Shu-jun
J Pediatr Endocrinol Metab. 2015 May;28(5-6):629-33. doi: 10.1515/jpem-2014-0250.
Vitamin D deficiency (VDD) in children is widespread. Therefore, the present study was conducted to assess the prevalence of VDD in schoolchildren from Henan Province, China.
The study was conducted on school students from areas of Xinxiang, one of the largest cities of Henan Province in China, in the winter of 2013. A questionnaire on demographic data, socioeconomic status, sun exposure, and times of acute respiratory infections (RTI) in the past 12 months were completed for each student. Blood samples were taken to assess serum levels of 25-hydroxyvitamin D [25(OH)D].
In our study, 606 schoolchildren completed the questionnaire. The median serum level of 25(OH)D was 20.5 ng/mL (interquartile range: 15.9-25.1). The prevalence of VDD and insufficiency was 46.9% (284/606) and 85.8% (520/606), respectively. VDD was more associated with female gender, high body mass index, lower socio-professional status, residence in urban areas, and less time spent outdoors. There was an inverse correlation between levels of 25(OH) and times of RTI (p<0.001).
VDD and insufficiency are common among schoolchildren in Xinxiang. Supplementation with food fortification or vitamin D for Chinese children is warranted.
儿童维生素D缺乏(VDD)现象普遍。因此,本研究旨在评估中国河南省学童中VDD的患病率。
本研究于2013年冬季对来自中国河南省最大城市之一新乡地区的在校学生进行。为每名学生填写了一份关于人口统计学数据、社会经济状况、阳光暴露情况以及过去12个月内急性呼吸道感染(RTI)次数的问卷。采集血样以评估血清25-羟基维生素D[25(OH)D]水平。
在我们的研究中,606名学童完成了问卷。25(OH)D的血清中位数水平为20.5 ng/mL(四分位间距:15.9 - 25.1)。VDD和维生素D不足的患病率分别为46.9%(284/606)和85.8%(520/606)。VDD与女性性别、高体重指数、较低的社会职业地位、居住在城市地区以及户外活动时间较少更相关。25(OH)水平与RTI次数呈负相关(p<0.001)。
VDD和维生素D不足在新乡学童中很常见。对中国儿童进行食物强化或补充维生素D是必要的。