Casado Verónica, Navarro Sandra M, Alvarez Andrés E, Villafañe Mercedes, Miranda Ana, Spaans Natalia
Parquesol Teaching Health Center, West Valladolid Multiprofessional Family and Communitary Care Teaching Unit, Valladolid, Spain
Parquesol Teaching Health Center, West Valladolid Multiprofessional Family and Communitary Care Teaching Unit, Valladolid, Spain.
Ann Fam Med. 2015 Jan-Feb;13(1):49-52. doi: 10.1370/afm.1733.
The purpose of this study was to evaluate sensitivity, specificity, and positive and negative likelihood ratios of laryngeal height, lung function, and diagnostic questionnaires for screening and diagnosis of chronic obstructive pulmonary disease (COPD).
We undertook a cross-sectional study of 233 people aged between 40 and 75 years. Measured variables were age, sex, weight, height, body mass index, tobacco use, maximum laryngeal height, and spirometry, and we administered a COPD questionnaire and the Lung Function Questionnaire.
For laryngeal height, we found a positive likelihood ratio of 5.21, and for the Lung Function Questionnaire, we found a negative likelihood ratio of 0.10. Combining a maximum laryngeal height of ≤4 cm with Lung Function Questionnaire findings of ≤18 yielded a positive likelihood ratio of 29.06, and a negative likelihood ratio of 0.26.
The intrinsic validity of the lung function questionnaire makes it useful for screening. Combining Lung Function Questionnaire results and laryngeal height can help confirm or dismiss COPD.
本研究旨在评估喉高、肺功能及诊断问卷对慢性阻塞性肺疾病(COPD)筛查和诊断的敏感性、特异性、阳性似然比和阴性似然比。
我们对233名年龄在40至75岁之间的人群进行了一项横断面研究。测量的变量包括年龄、性别、体重、身高、体重指数、吸烟情况、最大喉高和肺量计测量结果,我们还发放了一份COPD问卷和肺功能问卷。
对于喉高,我们发现阳性似然比为5.21;对于肺功能问卷,我们发现阴性似然比为0.10。将最大喉高≤4 cm与肺功能问卷结果≤18相结合,得到阳性似然比为29.06,阴性似然比为0.26。
肺功能问卷的内在效度使其适用于筛查。结合肺功能问卷结果和喉高有助于确诊或排除COPD。