相似文献
1
Compound signature detection on LINCS L1000 big data.
Mol Biosyst. 2015 Mar;11(3):714-22. doi: 10.1039/c4mb00677a. Epub 2015 Jan 22.
2
Drug Signature Detection Based on L1000 Genomic and Proteomic Big Data.
Methods Mol Biol. 2019;1939:273-286. doi: 10.1007/978-1-4939-9089-4_15.
3
Drug Effect Prediction by Integrating L1000 Genomic and Proteomic Big Data.
Methods Mol Biol. 2019;1939:287-297. doi: 10.1007/978-1-4939-9089-4_16.
4
Drug and disease signature integration identifies synergistic combinations in glioblastoma.
Nat Commun. 2018 Dec 14;9(1):5315. doi: 10.1038/s41467-018-07659-z.
5
Getting Started with LINCS Datasets and Tools.
Curr Protoc. 2022 Jul;2(7):e487. doi: 10.1002/cpz1.487.
6
Systematic Quality Control Analysis of LINCS Data.
CPT Pharmacometrics Syst Pharmacol. 2016 Nov;5(11):588-598. doi: 10.1002/psp4.12107. Epub 2016 Oct 31.
7
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W449-60. doi: 10.1093/nar/gku476. Epub 2014 Jun 6.
8
A Bayesian approach to accurate and robust signature detection on LINCS L1000 data.
Bioinformatics. 2020 May 1;36(9):2787-2795. doi: 10.1093/bioinformatics/btaa064.
9
L1000CDS: LINCS L1000 characteristic direction signatures search engine.
NPJ Syst Biol Appl. 2016;2:16015-. doi: 10.1038/npjsba.2016.15. Epub 2016 Aug 4.
10
DOSE-L1000: unveiling the intricate landscape of compound-induced transcriptional changes.
Bioinformatics. 2023 Nov 1;39(11). doi: 10.1093/bioinformatics/btad683.
引用本文的文献
1
CDCM: a correlation-dependent connectivity map approach to rapidly screen drugs during outbreaks of infectious diseases.
Brief Bioinform. 2024 Nov 22;26(1). doi: 10.1093/bib/bbae659.
2
Multivariate genome-wide association meta-analysis of over 1 million subjects identifies loci underlying multiple substance use disorders.
Nat Ment Health. 2023 Mar;1(3):210-223. doi: 10.1038/s44220-023-00034-y. Epub 2023 Mar 22.
3
Combination of antidepressants and antipsychotics as a novel treatment option for psychosis in Alzheimer's disease.
CPT Pharmacometrics Syst Pharmacol. 2023 Aug;12(8):1119-1131. doi: 10.1002/psp4.12979. Epub 2023 May 11.
4
Chemical-induced gene expression ranking and its application to pancreatic cancer drug repurposing.
Patterns (N Y). 2022 Feb 4;3(4):100441. doi: 10.1016/j.patter.2022.100441. eCollection 2022 Apr 8.
5
Oklahoma Nathan Shock Aging Center - assessing the basic biology of aging from genetics to protein and function.
Geroscience. 2021 Oct;43(5):2183-2203. doi: 10.1007/s11357-021-00454-7. Epub 2021 Oct 4.
6
Precision omics data integration and analysis with interoperable ontologies and their application for COVID-19 research.
Brief Funct Genomics. 2021 Jul 17;20(4):235-248. doi: 10.1093/bfgp/elab029.
7
Crinet: A computational tool to infer genome-wide competing endogenous RNA (ceRNA) interactions.
PLoS One. 2021 May 13;16(5):e0251399. doi: 10.1371/journal.pone.0251399. eCollection 2021.
8
Multi-Omics Analysis of Brain Metastasis Outcomes Following Craniotomy.
Front Oncol. 2021 Apr 6;10:615472. doi: 10.3389/fonc.2020.615472. eCollection 2020.
9
A deep learning framework for high-throughput mechanism-driven phenotype compound screening and its application to COVID-19 drug repurposing.
Nat Mach Intell. 2021 Mar;3(3):247-257. doi: 10.1038/s42256-020-00285-9. Epub 2021 Feb 1.
10
Drug-induced cell viability prediction from LINCS-L1000 through WRFEN-XGBoost algorithm.
BMC Bioinformatics. 2021 Jan 6;22(1):13. doi: 10.1186/s12859-020-03949-w.
本文引用的文献
1
LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.
Nucleic Acids Res. 2014 Jul;42(Web Server issue):W449-60. doi: 10.1093/nar/gku476. Epub 2014 Jun 6.
2
Large-scale prediction and testing of drug activity on side-effect targets.
Nature. 2012 Jun 10;486(7403):361-7. doi: 10.1038/nature11159.
3
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies.
J Clin Invest. 2011 Jul;121(7):2750-67. doi: 10.1172/JCI45014.
4
Learning lessons from Pfizer's $800 million failure.
Nat Rev Drug Discov. 2011 Mar;10(3):163-4. doi: 10.1038/nrd3401.
5
Constitutive androstane receptor agonist CITCO inhibits growth and expansion of brain tumour stem cells.
Br J Cancer. 2011 Feb 1;104(3):448-59. doi: 10.1038/sj.bjc.6606064. Epub 2011 Jan 11.
6
Principles of early drug discovery.
Br J Pharmacol. 2011 Mar;162(6):1239-49. doi: 10.1111/j.1476-5381.2010.01127.x.
7
ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.
Bioinformatics. 2010 Oct 1;26(19):2438-44. doi: 10.1093/bioinformatics/btq466. Epub 2010 Aug 13.
8
GOSemSim: an R package for measuring semantic similarity among GO terms and gene products.
Bioinformatics. 2010 Apr 1;26(7):976-8. doi: 10.1093/bioinformatics/btq064. Epub 2010 Feb 23.
9
Dietary feeding of dibenzoylmethane inhibits prostate cancer in transgenic adenocarcinoma of the mouse prostate model.
Cancer Res. 2009 Sep 1;69(17):7096-102. doi: 10.1158/0008-5472.CAN-09-0597. Epub 2009 Aug 25.
10
Discovery and structural analysis of Eph receptor tyrosine kinase inhibitors.
Bioorg Med Chem Lett. 2009 Aug 1;19(15):4467-70. doi: 10.1016/j.bmcl.2009.05.029. Epub 2009 May 13.
Zotero 插件