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霍奇金淋巴瘤幸存者的继发性癌症:一例病例报告及文献综述

Secondary cancer in a survivor of Hodgkin's lymphoma: A case report and review of the literature.

作者信息

Lisik-Habib Maja, Czernek Urszula, Dębska-Szmich Sylwia, Krakowska Magdalena, Kubicka-Wołkowska Joanna, Potemski Piotr

机构信息

Department of Chemotherapy, Medical University of Lodz, Copernicus Memorial Hospital, Lodz 93-513, Poland.

出版信息

Oncol Lett. 2015 Feb;9(2):964-966. doi: 10.3892/ol.2014.2799. Epub 2014 Dec 12.

Abstract

Hodgkin's lymphoma (HL) is one of the most curable malignant diseases in adults. However, HL patients have a higher risk of developing second malignancies compared with the general population. The population of adult cancer survivors is growing, thus, the long-term effects of cancer treatment, including secondary cancer development, have become an increasingly important concern in the field of oncology. The current study presents the case of a female HL survivor who developed two secondary malignancies within 29 years of follow-up. Furthermore, a review of the literature was conducted, which focused on secondary breast and gastrointestinal cancers in HL survivors.

摘要

霍奇金淋巴瘤(HL)是成人中最可治愈的恶性疾病之一。然而,与普通人群相比,HL患者发生第二原发性恶性肿瘤的风险更高。成年癌症幸存者的数量正在增加,因此,癌症治疗的长期影响,包括继发性癌症的发生,已成为肿瘤学领域日益重要的关注点。本研究报告了一名女性HL幸存者的病例,该患者在29年的随访期内发生了两种继发性恶性肿瘤。此外,还对文献进行了综述,重点关注HL幸存者中的继发性乳腺癌和胃肠道癌。

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