Research Centre of Immunology and Institute of Medical Microbiology and Hygiene, University of Mainz Medical Centre, Obere Zahlbacher Strasse 67, D-55131 Mainz, Germany.
Research Centre of Immunology and Institute of Medical Microbiology and Hygiene, University of Mainz Medical Centre, Obere Zahlbacher Strasse 67, D-55131 Mainz, Germany.
Cell Metab. 2015 Feb 3;21(2):152-153. doi: 10.1016/j.cmet.2015.01.015.
White-to-beige conversion of adipocytes is one of the most promising approaches to therapeutically target obesity; however, the signals driving this process had largely remained unclear. Recently, two publications, Brestoff et al. (2014) in Nature and Lee et al. (2015) in Cell, showed that group 2 innate lymphoid cells directly regulate adipocyte differentiation and drive the growth of beige fat.
白色脂肪米色化是治疗肥胖症最有前景的方法之一；然而，驱动这一过程的信号在很大程度上仍不清楚。最近，两篇出版物，Brestoff 等人（2014 年）在《自然》杂志和 Lee 等人（2015 年）在《细胞》杂志上的研究表明，2 型固有淋巴细胞直接调节脂肪细胞分化，并驱动米色脂肪的生长。
