凝聚相，含卤素键的 CF3I 和 C2F5I 加合物，用于全氟烷基化反应。
Condensed-phase, halogen-bonded CF3I and C2F5I adducts for perfluoroalkylation reactions.
机构信息
Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford St., Cambridge, MA 02138 (USA) http://rittergroup.org.
出版信息
Angew Chem Int Ed Engl. 2015 Mar 16;54(12):3712-6. doi: 10.1002/anie.201410954. Epub 2015 Feb 4.
PMID:25651531
Abstract
A family of practical, liquid trifluoromethylation and pentafluoroethylation reagents is described. We show how halogen bonding can be used to obtain easily handled liquid reagents from gaseous CF3I and CF3CF2I. The synthetic utility of the new reagents is exemplified by a novel direct arene trifluoromethylation reaction as well as adaptations of other perfluoroalkylation reactions.
摘要
描述了一类实用的液态三氟甲基化和五氟乙基化试剂。我们展示了如何利用卤素键将气态 CF3I 和 CF3CF2I 转化为易于处理的液态试剂。新试剂的合成用途包括新型芳基直接三氟甲基化反应以及其他全氟烷基化反应的改进。
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