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伴有“口鼻部”肿胀的非典型黑热病后皮肤利什曼病

Atypical post kala azar dermal leishmaniasis with "muzzle area" swelling.

作者信息

Arora Sandeep, Bal Arvinder Singh, Baveja Sukriti, Sood Aradhana, Rathi Khushi Ram, Patil Pradeep

机构信息

Department of Skin, Army College of Medical Sciences and Base Hospital, Cantt, New Delhi, India.

Department of Pathology, Army College of Medical Sciences and Base Hospital, Cantt, New Delhi, India.

出版信息

Indian J Dermatol. 2015 Jan-Feb;60(1):88-90. doi: 10.4103/0019-5154.147809.

Abstract

A 50-year-old male presented with recurrent swelling of the muzzle area of the face with history of low-grade intermittent fever of 3 year duration managed variously with antibiotics, systemic steroids, and antituberculous therapy. Skin biopsy revealed a granulomatous infiltration negative for acid-fast bacilli and leishmania donovan bodies. Immunochromatography test for rK 39 antigen and polymerase chain reaction for leishmania was positive. He was diagnosed as a case of post kala azar dermal leishmaniasis, managed with injection sodium stibogluconate and followed-up thereafter.

摘要

一名50岁男性,面部口鼻区域反复肿胀,伴有持续3年的低热间歇性发热病史,曾先后接受抗生素、全身性类固醇及抗结核治疗。皮肤活检显示为肉芽肿性浸润,抗酸杆菌和杜氏利什曼原虫均为阴性。rK 39抗原免疫层析试验及利什曼原虫聚合酶链反应呈阳性。他被诊断为黑热病后皮肤利什曼病,接受葡萄糖酸锑钠注射治疗,此后进行随访。

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