Basa Johanna V, Singh Lilly, Jaoude Wassim Abi, Sugiyama Gainosuke
SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 40, Brooklyn, NY 11203, United States.
SUNY Downstate Medical Center, 450 Clarkson Avenue, Box 40, Brooklyn, NY 11203, United States.
Int J Surg Case Rep. 2015;8C:117-9. doi: 10.1016/j.ijscr.2014.10.050. Epub 2014 Dec 23.
There are few cases of isolated splenic tuberculosis reported in the literature internationally, and nearly none from western medical centers. The incidence of tuberculosis has declined in the United States since the 1950s, with 11,585 reported cases in 2009, 21% of which were exclusively extrapulmonary. Splenic tuberculosis occurs mostly as part of miliary tuberculosis in immunocompromised patients. Isolated splenic tuberculosis is extremely rare, particularly in the immunocompetent patient. Patients susceptible to acquiring splenic tuberculosis usually have one of the following risk factors: immunosuppression, preceding pyogenic infections, splenic abnormalities, prior trauma to the spleen, sickle cell disease and other hemopathies, and in the immunocompetent patient another body site infected by M. tuberculosis. In this report we present the case of a young immunocompetent male with no other significant past medical history with isolated splenic tuberculosis.
国际文献中报道的孤立性脾结核病例很少,西方医学中心几乎没有相关报道。自20世纪50年代以来,美国的结核病发病率有所下降,2009年报告了11585例病例,其中21%为肺外结核。脾结核大多发生在免疫功能低下患者的粟粒性结核中。孤立性脾结核极为罕见,尤其是在免疫功能正常的患者中。易患脾结核的患者通常有以下危险因素之一:免疫抑制、先前的化脓性感染、脾脏异常、脾脏先前受过创伤、镰状细胞病和其他血液病,以及在免疫功能正常的患者中,身体其他部位感染结核分枝杆菌。在本报告中,我们介绍了一例年轻的免疫功能正常男性病例,他没有其他重大既往病史,患有孤立性脾结核。