脓毒症患者的早期抗生素治疗——里程碑还是关键点？
The early antibiotic therapy in septic patients--milestone or sticking point?
作者信息
Bernhard Michael, Lichtenstern Christoph, Eckmann Christian, Weigand Markus A
出版信息
Crit Care. 2014 Nov 30;18(6):671. doi: 10.1186/s13054-014-0671-1.
Abstract
Sepsis is one of the oldest and most elusive syndromes in medicine. Every effort should be made to treat these patients with the best available evidence. As a milestone, empiric antimicrobial therapy is essential in order to reduce morbidity and mortality of septic patients. As a sticking point, the use of broad-spectrum antimicrobial agents may be associated with induction of resistance among common pathogens.
摘要
脓毒症是医学领域中最古老且最难捉摸的综合征之一。应尽一切努力依据现有最佳证据来治疗这些患者。作为一个关键节点，经验性抗菌治疗对于降低脓毒症患者的发病率和死亡率至关重要。然而，一个棘手的问题是，使用广谱抗菌药物可能会导致常见病原体产生耐药性。
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