Grueva Em
Akush Ginekol (Sofiia). 2014;53(7):3-8.
A short review of the biological and epidemiological established causal role of human papillomavirus (HPV) in all types of cervical cancer most cancers of the vagina and anus of the cancer of the vulva, penis, and oropharynx, as and other types of cancer causally related to HPV such as skin cancer, melanoma and cancers of the conjunctiva exposure of other sexually transmissible infections (STD), such as Chlamydia trachomatis as co-factors that modify risk are required for transfer of cervical HPV infection to cancer.
By comparing changes in smears in Papanycolau /PAP/ patients with chlamydial and nehlamidialen endotservitsit to assess the involvement of Chlamydia trachomatis as a cofactor for the development of cancer.
Prospective study results direct immunofluorescence study /DIF/ for Chlamydia trachomatis and results in PAP smears.
708 patients were sexually active at the age of 16 to 65 years, classified by age 16 to 19, 20 to 29, 30 to 65, with a proven endotservitsit of gynecological examination, with studies made Chlamydia trachomatis /DIF/, a smear Pap.
There is no difference between the average values of cytology of patients in the PAP I and PAP II, positive Chl. trachomatis, ie., And that it is statistically insignificant. The number of patients with Chl. trachomatis, PAP II /positive/, more than the number of patients with Chlamydia trachomatis PAP I /positive/ Having inflammatory changes in smear of PAP II-82/65.6% compared with PAP I-36 pieces /28.8%/ shows that two thirds of patients positive for Chl.trachomatis, have cytology PAP II. Patients with PAP IV, IV-V are in the group of Chlamydia trachomatis /negative/. These are lacking in the group of Chlamydia trachomatis /positive/. Our results give us reason to conclude that Chlamydia trachomatis is not affected by co-factor prevalence of significant abnormalities in the cervical smear, but inflammatory changes in cytology may be the result of infection with C. trachomatis
简要回顾人乳头瘤病毒(HPV)在各类宫颈癌、大多数阴道癌、肛门癌、外阴癌、阴茎癌和口咽癌以及其他与HPV有因果关系的癌症(如皮肤癌、黑色素瘤和结膜癌)中已确立的生物学和流行病学因果作用,还需提及其他性传播感染(STD)(如沙眼衣原体)作为改变风险的辅助因素在宫颈HPV感染发展为癌症过程中的作用。
通过比较巴氏涂片检查(Papanycolau/PAP)中沙眼衣原体和非沙眼衣原体子宫内膜炎患者涂片的变化,评估沙眼衣原体作为癌症发展辅助因素的参与情况。
前瞻性研究,采用沙眼衣原体直接免疫荧光研究(DIF)结果和PAP涂片结果。
708名年龄在16至65岁的性活跃患者,按年龄分为16至19岁、20至29岁、30至65岁组,经妇科检查确诊为子宫内膜炎,进行沙眼衣原体(DIF)和巴氏涂片检查。
PAP I和PAP II组中沙眼衣原体呈阳性的患者细胞学平均值无差异,即统计学上无显著意义。沙眼衣原体呈阳性的PAP II组患者数量多于沙眼衣原体呈阳性的PAP I组患者数量。PAP II涂片有炎症变化的患者为82例(65.6%),而PAP I为36例(28.8%),这表明沙眼衣原体呈阳性的患者中有三分之二的细胞学检查为PAP II。PAP IV、IV - V组患者沙眼衣原体呈阴性。沙眼衣原体呈阳性组中没有此类患者。我们的结果使我们有理由得出结论,沙眼衣原体不受宫颈涂片显著异常患病率辅助因素的影响,但细胞学上的炎症变化可能是沙眼衣原体感染的结果