白细胞介素-1监视着守护者。 - Suppr

IL-1 watches the watchmen.

作者信息

Villarino Alejandro V, Laurence Arian

机构信息

Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA.

Northern Centre for Cancer Care, Freeman Hospital, Newcastle Upon Tyne, UK.

出版信息

Nat Immunol. 2015 Mar;16(3):226-7. doi: 10.1038/ni.3105.

DOI:10.1038/ni.3105

PMID:25689436

Abstract

摘要

相似文献

IL-1 watches the watchmen.

Nat Immunol. 2015 Mar;16(3):226-7. doi: 10.1038/ni.3105.

All in (IL-) 1?

Transplantation. 2015 Nov;99(11):2235-6. doi: 10.1097/TP.0000000000000966.

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.

Nat Immunol. 2015 Mar;16(3):286-95. doi: 10.1038/ni.3099. Epub 2015 Feb 2.

Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells.

Arthritis Rheum. 2012 Nov;64(11):3543-52. doi: 10.1002/art.34601.

Prostaglandin I2-IP signalling regulates human Th17 and Treg cell differentiation.

Prostaglandins Leukot Essent Fatty Acids. 2013 Oct;89(5):335-44. doi: 10.1016/j.plefa.2013.08.006. Epub 2013 Aug 30.

Reciprocal roles of STAT3 and STAT5 in nasal polyposis.

Am J Otolaryngol. 2012 Nov-Dec;33(6):741-52. doi: 10.1016/j.amjoto.2012.07.009. Epub 2012 Sep 5.

Oncostatin M Suppresses Activation of IL-17/Th17 via SOCS3 Regulation in CD4+ T Cells.

J Immunol. 2017 Feb 15;198(4):1484-1491. doi: 10.4049/jimmunol.1502314. Epub 2017 Jan 16.

p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.

Arthritis Rheum. 2013 Apr;65(4):949-59. doi: 10.1002/art.37841.

Modulation of STAT3 and STAT5 activity rectifies the imbalance of Th17 and Treg cells in patients with acute coronary syndrome.

Clin Immunol. 2015 Mar;157(1):65-77. doi: 10.1016/j.clim.2014.12.012. Epub 2015 Jan 5.

IL-2 activation of STAT5 enhances production of IL-10 from human cytotoxic regulatory T cells, HOZOT.

Exp Hematol. 2008 Feb;36(2):181-92. doi: 10.1016/j.exphem.2007.09.010. Epub 2007 Nov 26.

引用本文的文献

Interleukin-1 as Innate Mediator of T Cell Immunity.

Front Immunol. 2021 Jan 27;11:621931. doi: 10.3389/fimmu.2020.621931. eCollection 2020.

SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension.

Front Physiol. 2018 Nov 15;9:1581. doi: 10.3389/fphys.2018.01581. eCollection 2018.

Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation.

Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5. doi: 10.1016/j.chom.2017.10.008.

本文引用的文献

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.

Nat Immunol. 2015 Mar;16(3):286-95. doi: 10.1038/ni.3099. Epub 2015 Feb 2.

The role of inflammasome-derived IL-1 in driving IL-17 responses.

J Leukoc Biol. 2013 Apr;93(4):489-97. doi: 10.1189/jlb.1012543. Epub 2012 Dec 27.

Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile.

Nat Immunol. 2012 Mar 11;13(4):405-11. doi: 10.1038/ni.2242.

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages.

Nat Immunol. 2011 Jun;12(6):551-9. doi: 10.1038/ni.2030. Epub 2011 Apr 24.

Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha.

Immunity. 2011 Mar 25;34(3):435-47. doi: 10.1016/j.immuni.2011.03.003.

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

Nat Immunol. 2011 Mar;12(3):247-54. doi: 10.1038/ni.1995. Epub 2011 Jan 30.

Th17 and regulatory T cells in mediating and restraining inflammation.

Cell. 2010 Mar 19;140(6):845-58. doi: 10.1016/j.cell.2010.02.021.

Differential regulation of Foxp3 and IL-17 expression in CD4 T helper cells by IRAK-1.

J Immunol. 2009 May 1;182(9):5763-9. doi: 10.4049/jimmunol.0900124.

Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+ T cell pool IL-1 subverts IL-2-mediated suppression.

J Immunol. 2007 Aug 1;179(3):1423-6. doi: 10.4049/jimmunol.179.3.1423.

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

Science. 2007 Jul 13;317(5835):256-60. doi: 10.1126/science.1145697. Epub 2007 Jun 14.

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IL-1 watches the watchmen.

作者信息

Villarino Alejandro V, Laurence Arian

机构信息

Molecular Immunology and Inflammation Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, NIH, Bethesda, Maryland, USA.

Northern Centre for Cancer Care, Freeman Hospital, Newcastle Upon Tyne, UK.

出版信息

Nat Immunol. 2015 Mar;16(3):226-7. doi: 10.1038/ni.3105.

DOI:10.1038/ni.3105

PMID:25689436

Abstract

摘要

相似文献

IL-1 watches the watchmen.

Nat Immunol. 2015 Mar;16(3):226-7. doi: 10.1038/ni.3105.

All in (IL-) 1?

Transplantation. 2015 Nov;99(11):2235-6. doi: 10.1097/TP.0000000000000966.

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.

Nat Immunol. 2015 Mar;16(3):286-95. doi: 10.1038/ni.3099. Epub 2015 Feb 2.

Modulation of STAT-3 in rheumatoid synovial T cells suppresses Th17 differentiation and increases the proportion of Treg cells.

Arthritis Rheum. 2012 Nov;64(11):3543-52. doi: 10.1002/art.34601.

Prostaglandin I2-IP signalling regulates human Th17 and Treg cell differentiation.

Prostaglandins Leukot Essent Fatty Acids. 2013 Oct;89(5):335-44. doi: 10.1016/j.plefa.2013.08.006. Epub 2013 Aug 30.

Reciprocal roles of STAT3 and STAT5 in nasal polyposis.

Am J Otolaryngol. 2012 Nov-Dec;33(6):741-52. doi: 10.1016/j.amjoto.2012.07.009. Epub 2012 Sep 5.

Oncostatin M Suppresses Activation of IL-17/Th17 via SOCS3 Regulation in CD4+ T Cells.

J Immunol. 2017 Feb 15;198(4):1484-1491. doi: 10.4049/jimmunol.1502314. Epub 2017 Jan 16.

p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice.

Arthritis Rheum. 2013 Apr;65(4):949-59. doi: 10.1002/art.37841.

Modulation of STAT3 and STAT5 activity rectifies the imbalance of Th17 and Treg cells in patients with acute coronary syndrome.

Clin Immunol. 2015 Mar;157(1):65-77. doi: 10.1016/j.clim.2014.12.012. Epub 2015 Jan 5.

IL-2 activation of STAT5 enhances production of IL-10 from human cytotoxic regulatory T cells, HOZOT.

Exp Hematol. 2008 Feb;36(2):181-92. doi: 10.1016/j.exphem.2007.09.010. Epub 2007 Nov 26.

引用本文的文献

Interleukin-1 as Innate Mediator of T Cell Immunity.

Front Immunol. 2021 Jan 27;11:621931. doi: 10.3389/fimmu.2020.621931. eCollection 2020.

SGK1-FoxO1 Signaling Pathway Mediates Th17/Treg Imbalance and Target Organ Inflammation in Angiotensin II-Induced Hypertension.

Front Physiol. 2018 Nov 15;9:1581. doi: 10.3389/fphys.2018.01581. eCollection 2018.

Staphylococcus aureus Virulent PSMα Peptides Induce Keratinocyte Alarmin Release to Orchestrate IL-17-Dependent Skin Inflammation.

Cell Host Microbe. 2017 Nov 8;22(5):667-677.e5. doi: 10.1016/j.chom.2017.10.008.

本文引用的文献

IL-1 signaling modulates activation of STAT transcription factors to antagonize retinoic acid signaling and control the TH17 cell-iTreg cell balance.

Nat Immunol. 2015 Mar;16(3):286-95. doi: 10.1038/ni.3099. Epub 2015 Feb 2.

The role of inflammasome-derived IL-1 in driving IL-17 responses.

J Leukoc Biol. 2013 Apr;93(4):489-97. doi: 10.1189/jlb.1012543. Epub 2012 Dec 27.

Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile.

Nat Immunol. 2012 Mar 11;13(4):405-11. doi: 10.1038/ni.2242.

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages.

Nat Immunol. 2011 Jun;12(6):551-9. doi: 10.1038/ni.2030. Epub 2011 Apr 24.

Essential role for retinoic acid in the promotion of CD4(+) T cell effector responses via retinoic acid receptor alpha.

Immunity. 2011 Mar 25;34(3):435-47. doi: 10.1016/j.immuni.2011.03.003.

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5.

Nat Immunol. 2011 Mar;12(3):247-54. doi: 10.1038/ni.1995. Epub 2011 Jan 30.

Th17 and regulatory T cells in mediating and restraining inflammation.

Cell. 2010 Mar 19;140(6):845-58. doi: 10.1016/j.cell.2010.02.021.

Differential regulation of Foxp3 and IL-17 expression in CD4 T helper cells by IRAK-1.

J Immunol. 2009 May 1;182(9):5763-9. doi: 10.4049/jimmunol.0900124.

Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+ T cell pool IL-1 subverts IL-2-mediated suppression.

J Immunol. 2007 Aug 1;179(3):1423-6. doi: 10.4049/jimmunol.179.3.1423.

Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid.

Science. 2007 Jul 13;317(5835):256-60. doi: 10.1126/science.1145697. Epub 2007 Jun 14.

IL-1 watches the watchmen.

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IL-1 watches the watchmen.

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