辅助性部分原位肝移植中的门静脉血流调节

Portal flow modulation in auxiliary partial orthotopic liver transplantation.

作者信息

Rela Mohamed, Bharathan Anand, Palaniappan Kumar, Cherian Pradeep T, Reddy Mettu S

机构信息

Institute of Liver Disease & Transplantation, Global Hospital & Health City, National Foundation for Liver Research, Chennai, Tamil Nadu, India; Institute of Liver Studies, Kings College Hospital, Denmark Hill, London, UK.

出版信息

Pediatr Transplant. 2015 May;19(3):255-60. doi: 10.1111/petr.12436. Epub 2015 Feb 18.

DOI:10.1111/petr.12436

PMID:25692474

Abstract

APOLT is a suitable technique of liver transplantation in patients with ALF and some types of MLD. Portal venous steal is a problem with this procedure that leads to graft dysfunction and failure. Modulation of the portal flow to the graft and native liver can help in preventing this problem. We discuss the pathophysiology of this complication, review available literature regarding its management, and describe our results using the technique of graded hemiportal banding to achieve adequate perfusion for the graft and native liver.

摘要

辅助部分原位肝移植（APOLT）是急性肝衰竭（ALF）患者和某些类型的代谢性肝病（MLD）患者进行肝移植的一种合适技术。门静脉盗血是该手术存在的一个问题，会导致移植物功能障碍和衰竭。调节进入移植物和自体肝脏的门静脉血流有助于预防这一问题。我们讨论了这种并发症的病理生理学，回顾了有关其处理的现有文献，并描述了我们使用分级半门静脉结扎技术为移植物和自体肝脏实现充分灌注的结果。