通过RNA聚合酶II羧基末端结构域协调转录 - Suppr

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Orchestrating transcription with the Pol II CTD.

作者信息

Conaway Ronald C, Conaway Joan W

机构信息

Stowers Institute for Medical Research 1000 E 50th St, Kansas City, Missouri 64110, USA.

出版信息

Nat Rev Mol Cell Biol. 2015 Mar;16(3):128. doi: 10.1038/nrm3956. Epub 2015 Feb 18.

DOI:10.1038/nrm3956

PMID:25693123

Abstract

摘要

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本文引用的文献

Messenger RNA synthesis in mammalian cells is catalyzed by the phosphorylated form of RNA polymerase II.

J Biol Chem. 1987 Sep 15;262(26):12468-74.

RNA contacts subunits IIo and IIc in HeLa RNA polymerase II transcription complexes.

J Biol Chem. 1986 Oct 25;261(30):14226-31.

Phosphorylation of RNA polymerase IIA occurs subsequent to interaction with the promoter and before the initiation of transcription.

J Biol Chem. 1990 Aug 5;265(22):13165-73.

The interaction of RNA polymerase II with the adenovirus-2 major late promoter is precluded by phosphorylation of the C-terminal domain of subunit IIa.

J Biol Chem. 1992 May 25;267(15):10500-6.

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