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一例妊娠试验阴性的异位妊娠破裂罕见病例——病例报告及文献简要回顾

A unique case of ruptured ectopic pregnancy in a patient with negative preg-nancy test - a case report and brief review of the literature.

作者信息

Daniilidis A, Pantelis A, Makris V, Balaouras D, Vrachnis N

机构信息

2 University Department of Obstetrics and Gynecology, Hippokrateio General Hospital, Aristotle University of Thessaloniki, Greece.

2 University Department of Obstetrics and Gynecology, Aretaieio General Hospital, Kapodistrian University of Athens, Greece.

出版信息

Hippokratia. 2014 Jul-Sep;18(3):282-4.

Abstract

INTRODUCTION

Despite the major advances made in the diagnosis and management of ectopic pregnancies in the last two decades, an accurate diagnosis can sometimes still be quite challenging, since it relies on the combination of ultrasound findings and serial serum beta-human chorionic gonadotrophin (β-hCG) measurements.

CASE PRESENTATION

This paper describes the case of a 36-year-old woman of Caucasian origin who was admitted to the emergency department of our clinic with clinical symptoms of hemorrhagic shock in combination with two negative pregnancy tests done by her at home and a negative urine test which was performed on her admission to the hospital. Quantitative measurement of β-hCG in the serum of the patient was 13 mIU/mL. On admission, right tubal pregnancy was diagnosed on ultrasound and she underwent an emergency laparotomy due to signs of hemodynamic shock.

CONCLUSION

It is sometimes a considerable challenge to identify a patient with an ectopic pregnancy at risk of rupture. This case of ectopic pregnancy which was followed by a negative pregnancy test illustrates the magnitude of the difficulties involved in the diagnosis of ectopic pregnancy. It also demonstrates the need to maintain a high clinical index of suspicion and to undertake careful clinical examination of the patient on the basis of the clinician's diagnostic research. Hippokratia 2014; 18 (3): 282-284.

摘要

引言

尽管在过去二十年中异位妊娠的诊断和管理取得了重大进展,但准确诊断有时仍颇具挑战性,因为它依赖于超声检查结果和血清β-人绒毛膜促性腺激素(β-hCG)系列测量结果的结合。

病例报告

本文描述了一名36岁的白种女性病例,她因出血性休克的临床症状被收治入我院急诊科,其在家中进行的两次妊娠试验均为阴性,入院时尿液检测也为阴性。患者血清β-hCG定量测量值为13 mIU/mL。入院时,超声诊断为右侧输卵管妊娠,由于存在血流动力学休克迹象,她接受了急诊剖腹手术。

结论

识别有破裂风险的异位妊娠患者有时是一项相当大的挑战。该例异位妊娠且妊娠试验为阴性的病例说明了异位妊娠诊断中所涉及困难的程度。它还表明需要保持高度的临床怀疑指数,并根据临床医生的诊断研究对患者进行仔细的临床检查。《希波克拉底》2014年;18(3):282 - 284。

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