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食管食物嵌塞的病因及处理:一项基于人群的研究。

Etiology and management of esophageal food impaction: a population based study.

作者信息

Gretarsdottir Helga M, Jonasson Jon Gunnlaugur, Björnsson Einar S

机构信息

Department of the Internal Medicine, Division of Gastroenterology and Hepatology, The National University Hospital of Iceland , Reykjavik , Iceland.

出版信息

Scand J Gastroenterol. 2015 May;50(5):513-8. doi: 10.3109/00365521.2014.983159. Epub 2015 Feb 22.

Abstract

OBJECTIVE

Esophageal food impaction (FI) is a common clinical problem with limited information on incidence. Previous population based studies are lacking. The incidence, main etiological factors, recurrence and outcome of FI was determined in the present study in a population based setting.

MATERIAL AND METHODS

This was a study of consecutive adult patients who presented with FI from 2008 to 2013 at the National University Hospital of Iceland. The mean crude incidence rate of FI was calculated. Retrospective analysis was undertaken on relevant clinical data such as type of bolus, management, complications, recurrence rate, risk factors for recurrence, and outcome.

RESULTS

Overall 308 patients had endoscopically confirmed FI, males 199/308 (65%), median age 62 years. The mean crude incidence was 25 per 100,000 inhabitants per year. The types of FI was meat (68%), fish (12%), vegetable (4%) and other food/objects (16%). Causes for the FI included: esophageal strictures (45%), hiatal hernia (22%), eosinophilic esophagitis (EoE) (16%) and esophageal carcinoma (2%). Recurrence appeared in 21%, in which 24/48 (50%) had EoE vs. 40/260 (15%) in others (p = 0.0001). The removal of the foreign body was successful in 98% of the cases during the first endoscopy. Endoscopic associated complications included four (1.3%) aspirations, one (0.3%) esophageal perforation and one Boerhaave syndrome at presentation (both had EoE).

CONCLUSIONS

The incidence of FI is the highest reported to date. EoE was strongly associated with recurrence of FI. In a population based setting endoscopy is a safe and effective procedure for removing FI.

摘要

目的

食管食物嵌塞(FI)是一个常见的临床问题,但关于其发病率的信息有限。以往缺乏基于人群的研究。本研究在基于人群的环境中确定了FI的发病率、主要病因、复发情况及结局。

材料与方法

这是一项对2008年至2013年在冰岛国立大学医院出现FI的连续成年患者的研究。计算了FI的平均粗发病率。对相关临床数据进行回顾性分析,如食团类型、处理方式、并发症、复发率、复发危险因素及结局。

结果

共有308例患者经内镜确诊为FI,男性199/308(65%),中位年龄62岁。平均粗发病率为每年每10万居民25例。FI的类型为肉类(68%)、鱼类(12%)、蔬菜(4%)和其他食物/物体(16%)。FI的病因包括:食管狭窄(45%)、食管裂孔疝(22%)、嗜酸性粒细胞性食管炎(EoE)(16%)和食管癌(2%)。21%出现复发,其中EoE患者24/48(50%)复发,其他患者40/260(15%)复发(p = 0.0001)。98%的病例在首次内镜检查时成功取出异物。内镜相关并发症包括4例(1.3%)误吸、1例(0.3%)食管穿孔和1例就诊时的Boerhaave综合征(均为EoE患者)。

结论

FI的发病率是迄今为止报道的最高值。EoE与FI的复发密切相关。在基于人群的环境中,内镜检查是取出FI的安全有效方法。

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