在阐明强迫症之谜方面向前迈进了一步。

A step forward in elucidating the mystery of OCD.

作者信息

Kohl Sina, Ebbert Lena, Sartorius Alexander, Kuhn Jens

机构信息

Department of Psychiatry and Psychotherapy, University Hospital Cologne, Cologne, Germany.

Department of Psychiatry and Psychotherapy, Medical Faculty Mannheim, Central Institute of Mental Health (CIMH), University of Heidelberg, Mannheim, Germany.

出版信息

Eur Arch Psychiatry Clin Neurosci. 2015 Dec;265(8):735-6. doi: 10.1007/s00406-015-0584-2. Epub 2015 Feb 24.

DOI:10.1007/s00406-015-0584-2

PMID:25708456

Abstract

Obsessive-compulsive disorder represents one of the most disabling psychiatric disorders. The underlying pathophysiology is not fully understood. In a recent Science article, Ahmari and colleagues enlighten fundamental aspects of obsessive-compulsive disorder by means of optogenetic stimulation, thereby also elucidating the usefulness of SSRI in the treatment for OCD.

摘要

强迫症是最具致残性的精神疾病之一。其潜在的病理生理学机制尚未完全明确。在最近发表于《科学》杂志的一篇文章中，阿马里及其同事通过光遗传学刺激揭示了强迫症的基本特征，同时也阐明了选择性5-羟色胺再摄取抑制剂（SSRI）在强迫症治疗中的作用。