康定橐吾中的萜类化合物。
Terpenoids from Ligularia kangtingensis.
作者信息
Tian Jin, Xie Guang-Bo, Xie Ya, Li Tie-Nan
机构信息
Department of Biotechnology, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, PR China.
出版信息
Pharmacogn Mag. 2015 Jan-Mar;11(41):44-7. doi: 10.4103/0973-1296.149702.
BACKGROUND
Ligularia kangtingensis, a species from the genus Ligularia (Compositae), is an indigenous plant in Southwest China and more than 20 species in this genus have been used as folk medicines in China.
OBJECTIVE
The chemical constituents of the whole plant of L. kangtingensis were studied.
MATERIALS AND METHODS
The dried whole plants were extracted with ethanol. Its chemical constituents were mainly isolated and purified by silica gel and Sephadex LH-20 column chromatography and their structures were identified on the basis of spectral analysis.
RESULTS
Twelve known terpenoids, including two monoterpenoids, five sesquiterpenoids and five triterpenoids, were isolated and identified from the whole plant of L. kangtingensis.
CONCLUSION
All of the 12 known compounds were isolated for the first time from L. kangtingensis.
背景
康定橐吾是菊科橐吾属的一种植物，是中国西南部的本土植物，该属20多种植物在中国被用作民间药物。
目的
研究康定橐吾全草的化学成分。
材料与方法
干燥的全草用乙醇提取。其化学成分主要通过硅胶和葡聚糖凝胶LH - 20柱色谱进行分离纯化，并根据光谱分析鉴定其结构。
结果
从康定橐吾全草中分离鉴定出12个已知萜类化合物，包括2个单萜、5个倍半萜和5个三萜。
结论
这12个已知化合物均首次从康定橐吾中分离得到。
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