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全膝关节置换术后复发性关节积血采用关节内注射钇-90治疗

Recurrent Hemarthroses After TKA Treated With an Intraarticular Injection of Yttrium-90.

作者信息

Fine Stephen, Klestov Alex

机构信息

Department of Orthopaedic Surgery, Greenslopes Private Hospital, Newdegate Street, Greenslopes, Brisbane, 4120, Australia.

Rheumatology Department, Royal Brisbane and Women's Hospital, Herston, Brisbane, Australia.

出版信息

Clin Orthop Relat Res. 2016 Mar;474(3):850-3. doi: 10.1007/s11999-015-4217-x. Epub 2015 Feb 25.

Abstract

BACKGROUND

Recurrent hemarthroses after a TKA are uncommon and usually respond to nonoperative treatment or intervention using angiographic embolization or synovectomy. However, in rare circumstances, the problem can be resistant to treatment.

CASE DESCRIPTION

We report the case of a patient who had recurrent hemarthroses after a TKA. During the first 18 months after surgery, the patient experienced 48 episodes consistent with bleeding into the knee. The bleeding episodes recurred despite use of traditional treatments, including arthroscopy, open synovectomy and embolization of a small, false aneurysm. The patient ultimately received an intraarticular injection of yttrium-90 silica/citrate, and the hemarthroses ceased soon after the injection. At last review, 25 months after the injection, the patient had experienced no additional bleeding episodes.

LITERATURE REVIEW

On review of the literature, we found only one other report in which yttrium-90 was used successfully in a similar situation.

CLINICAL RELEVANCE

Yttrium-90 may be considered a treatment option in patients with recurrent hemarthroses after TKA, especially when the condition has not responded to more traditional treatments. The long-term risk of treatment with yttrium-90 for recurrent hemarthroses after a TKA remains unclear.

摘要

背景

全膝关节置换术(TKA)后反复出现关节积血并不常见,通常对非手术治疗或采用血管造影栓塞或滑膜切除术的干预有效。然而,在极少数情况下,该问题可能对治疗有抵抗性。

病例描述

我们报告了1例TKA后反复出现关节积血的患者。在术后的最初18个月里,该患者经历了48次与膝关节出血相符的发作。尽管采用了包括关节镜检查、开放性滑膜切除术和小型假性动脉瘤栓塞在内的传统治疗方法,出血发作仍反复出现。该患者最终接受了钇-90二氧化硅/柠檬酸盐关节内注射,注射后不久关节积血停止。在最后一次复查时,即注射后25个月,该患者未再出现出血发作。

文献综述

在查阅文献时,我们仅发现另一篇报告,其中钇-90在类似情况下成功使用。

临床意义

对于TKA后反复出现关节积血的患者,尤其是当病情对更传统的治疗无反应时,钇-90可被视为一种治疗选择。TKA后反复出现关节积血采用钇-90治疗的长期风险尚不清楚。

相似文献

本文引用的文献

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Recurrent hemarthrosis after total knee arthroplasty.全膝关节置换术后反复关节内积血。
Knee Surg Sports Traumatol Arthrosc. 2010 Jul;18(7):898-900. doi: 10.1007/s00167-009-1031-6. Epub 2010 Jan 14.
8
Recurrent haemarthrosis following total knee replacement.全膝关节置换术后复发性关节积血
Knee. 2010 Jan;17(1):7-14. doi: 10.1016/j.knee.2009.06.008. Epub 2009 Jul 17.

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