Ida Mitsuru, Kawaguchi Masahiko
Masui. 2014 Nov;63(11):1228-34.
Postoperative cognitive dysfunction (POCD) is seen not only after cardiac surgery but also after non-cardiac surgery. POCD leads to decreased quality of life and increased mortality. Various reports describe the occurrence and risk factor of POCD in adopting different neuropsychological tests and different follow-up periods. POCD is highly associated with age or inflammation in the central nerve system. Anti-inflammatory strategies including dexmedetomidine, statin or minocycline in the perioperative period may reduce incidence of POCD.
术后认知功能障碍(POCD)不仅见于心脏手术后,也见于非心脏手术后。POCD会导致生活质量下降和死亡率增加。各种报告描述了采用不同神经心理学测试和不同随访期时POCD的发生情况及危险因素。POCD与年龄或中枢神经系统炎症高度相关。围手术期采用右美托咪定、他汀类药物或米诺环素等抗炎策略可能会降低POCD的发生率。