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中国新兴猪细小病毒的流行情况及其与猪圆环病毒2型的共感染情况

Prevalence of emerging porcine parvoviruses and their co-infections with porcine circovirus type 2 in China.

作者信息

Sun Jianhui, Huang Liping, Wei Yanwu, Wang Yiping, Chen Dongjie, Du Wenjuan, Wu Hongli, Liu Changming

机构信息

Division of Swine Infectious Diseases, State Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Harbin, 150001, China.

出版信息

Arch Virol. 2015 May;160(5):1339-44. doi: 10.1007/s00705-015-2373-7. Epub 2015 Mar 6.

DOI:10.1007/s00705-015-2373-7
PMID:25742931
Abstract

A total of 450 samples from domestic pigs in China were tested for porcine parvoviruses (PPVs) and co-infections with porcine circovirus type 2 (PCV2), and their complete capsid genes were sequenced. The prevalence of PPV1, PPV2, PPV3, PPV4, and PCV2 was 5.56 %, 39.56 %, 45.11 %, 21.56 %, and 47.33 %, respectively, and co-infection with PCV2 occurred in 4 % (PPV1), 22.44 % (PPV2), 24 % (PPV3), and 12 % (PPV4) of the samples. Phylogenetic analysis revealed two main lineages for each virus, and residues that differentiated these viruses were identified. The co-infections of emerging PPVs and PCV2 were prevalent, indicating their cooperative roles in porcine circovirus-associated diseases.

摘要

对来自中国家猪的450份样本进行了猪细小病毒(PPV)检测以及与猪圆环病毒2型(PCV2)的共感染检测,并对其完整的衣壳基因进行了测序。PPV1、PPV2、PPV3、PPV4和PCV2的流行率分别为5.56%、39.56%、45.11%、21.56%和47.33%,4%(PPV1)、22.44%(PPV2)、24%(PPV3)和12%(PPV4)的样本发生了与PCV2的共感染。系统发育分析揭示了每种病毒的两个主要谱系,并鉴定出区分这些病毒的残基。新出现的PPV与PCV2的共感染很普遍,表明它们在猪圆环病毒相关疾病中起协同作用。

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