Pedotti Rosetta, Losappio Laura, Farinotti Mariangela, Preziosi Donatella, Tramacere Irene, Stafylaraki Chrysi, Mascheri Ambra, Filippini Graziella, Pastorello Elide A
Rhinology. 2015 Mar;53(1):49-53. doi: 10.4193/Rhino14.057.
The assessment of allergic asthma (AA) and allergic rhinitis (AR) in epidemiological studies is often challenging. We performed a cross-sectional study to test the accuracy of a Questionnaire aimed at Identifying subjects with Respiratory Allergy (QIRA) in a simple and fast way.
One hundred-thirty subjects, 18-76 years of age, admitted consecutively at the Allergy Center of the Niguarda Ca` Granda Hospital of Milan were included. The questionnaire (index test) investigated the presence of AA and AR with seven questions enquiring history of symptoms, diagnosis made by a doctor, allergy tests performed, and treatments. After completing the questionnaire, all subjects were subsequently diagnosed by an allergist (reference standard).
The accuracy of the questionnaire for the diagnosis of AA and AR was high (sensitivity 94.7% [95% confidence interval CI: 74.0-99.9] and specificity 99.1% [95% CI 95.1-100.0] for AA; sensitivity 82.8% [95% CI 71.3-91.1] and specificity 98.5% [95% CI 91.8-100.0] for AR).
The questionnaire significantly distinguished subjects with respiratory allergy from those without. The QIRA represents a valid and accurate tool for classifying subjects as having or not AA and/or AR in epidemiological studies.
在流行病学研究中，评估过敏性哮喘（AA）和过敏性鼻炎（AR）往往具有挑战性。我们进行了一项横断面研究，以测试一份旨在以简单快速的方式识别呼吸道过敏受试者的问卷（QIRA）的准确性。
纳入了130名年龄在18 - 76岁之间、连续入住米兰尼瓜尔达·卡格兰达医院过敏中心的受试者。该问卷（指标测试）通过七个问题调查AA和AR的存在情况，这些问题涉及症状史、医生做出的诊断、进行的过敏测试以及治疗情况。完成问卷后，所有受试者随后由过敏症专科医生进行诊断（参考标准）。
该问卷对AA和AR诊断的准确性较高（AA的敏感性为94.7% [95%置信区间CI：74.0 - 99.9]，特异性为99.1% [95% CI 95.1 - 100.0]；AR的敏感性为82.8% [95% CI 71.3 - 91.1]，特异性为98.5% [95% CI 91.8 - 100.0]）。
该问卷能显著区分有呼吸道过敏的受试者和无呼吸道过敏的受试者。在流行病学研究中，QIRA是一种用于将受试者分类为患有或未患有AA和/或AR的有效且准确的工具。
Zotero 插件