Larrea Sara, Palència Laia, Perez Glòria
Departament de Ciències Experimentals i de la Salut, Universitat Pompeu Fabra, Barcelona, España.
CIBER de Epidemiología y Salud Pública (CIBERESP), España; Agència de Salut Pública de Barcelona, Barcelona, España.
Gac Sanit. 2015 May-Jun;29(3):198-204. doi: 10.1016/j.gaceta.2015.02.003. Epub 2015 Mar 12.
To analyze reported complications and their treatment after a medical abortion with mifepristone and misoprostol provided by a telemedicine service to women living in Latin America.
Observational study based on the registry of consultations in a telemedicine service. A total of 872 women who used the service in 2010 and 2011 participated in the study. The dependent variables were overall complications, hemorrhage, incomplete abortion, overall treatments, surgical evacuation, and antibiotics. Independent variables were age, area of residence, socioeconomic deprivation, previous children, pregnancies and abortions, and week of pregnancy. We fitted Poisson regression models with robust variance to estimate incidence ratios and 95% confidence intervals (95%CI).
Complications were reported by 14.6% of the participants: 6.2% reported hemorrhage and 6.8% incomplete abortion. Nearly one-fifth (19.0%) received postabortion treatment: 10.9% had a surgical evacuation and 9.3% took antibiotics. Socioeconomic deprivation increased the risk of complications by 64% (95%CI: 15%-132%), and, among these, the risk of incomplete abortion by 82% (95%CI: 8%-206%) and the risk of surgical intervention by 62% (95%CI: 7%-144%). Previous pregnancies increased the risk of complications and, specifically, the risk of hemorrhage by 2.29 times (95%CI: 1.33-3.95%). Women with a pregnancy of 12 or more weeks had a 2.45 times higher risk of receiving medical treatment and a 2.94 times higher risk of taking antibiotics compared with women with pregnancies of 7 or less weeks.
Medical abortion provided by telemedicine seems to be a safe and effective alternative in contexts where it is legally restricted.
分析远程医疗服务为拉丁美洲女性提供米非司酮和米索前列醇药物流产后的并发症报告及其治疗情况。
基于远程医疗服务咨询登记的观察性研究。共有872名在2010年和2011年使用该服务的女性参与了研究。因变量为总体并发症、出血、流产不全、总体治疗、手术清宫和抗生素使用情况。自变量为年龄、居住地区、社会经济贫困程度、既往子女数、怀孕和流产次数以及孕周。我们采用具有稳健方差的泊松回归模型来估计发病率比和95%置信区间(95%CI)。
14.6%的参与者报告有并发症:6.2%报告有出血,6.8%报告有流产不全。近五分之一(19.0%)的人接受了流产后治疗:10.9%进行了手术清宫,9.3%使用了抗生素。社会经济贫困使并发症风险增加64%(95%CI:15%-132%),其中流产不全风险增加82%(95%CI:8%-206%),手术干预风险增加62%(95%CI:7%-144%)。既往怀孕会增加并发症风险,特别是出血风险增加2.29倍(95%CI:1.33 - 3.95%)。与孕周7周及以下的女性相比,孕周12周及以上的女性接受药物治疗的风险高2.45倍,使用抗生素的风险高2.94倍。
在法律受限的情况下,远程医疗提供的药物流产似乎是一种安全有效的选择。