The Third Affiliated Hospital of Nantong University, Wuxi 214000, Jiangsu Province, China.
Neural Regen Res. 2012 Feb 25;7(6):434-9. doi: 10.3969/j.issn.1673-5374.2012.06.005.
Patients with mild cognitive impairment after a transient ischemic attack were included in this study. They were treated with Yizhi Xingnao prescription, ergoloid mesylates or aspirin for 60 days. Evaluation using the Montreal Cognitive Assessment Scale showed that cognitive function was significantly improved in all patients, especially after the combined treatment of Yizhi Xingnao and aspirin. The scores from the Montreal Cognitive Assessment Scale were improved overall and the effective treatment rate was as high as 79%, which was higher than patients treated with a combination of ergoloid mesylates and aspirin, or aspirin alone. Our experimental findings indicate that Yizhi Xingnao prescription can improve mild cognitive impairment after a transient ischemic attack, and that it is more effective than ergoloid mesylates.
本研究纳入了短暂性脑缺血发作后轻度认知障碍的患者。他们分别接受益智醒脑方、茴拉西坦或阿司匹林治疗 60 天。采用蒙特利尔认知评估量表进行评估，结果显示所有患者的认知功能均显著改善，益智醒脑方联合阿司匹林治疗效果更为显著。蒙特利尔认知评估量表评分总体改善，有效治疗率高达 79%，明显高于茴拉西坦联合阿司匹林或阿司匹林单独治疗的患者。本实验结果表明，益智醒脑方可改善短暂性脑缺血发作后轻度认知障碍，且疗效优于茴拉西坦。
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