Mira José Joaquín, Lorenzo Susana, Guilabert Mercedes, Navarro Isabel, Pérez-Jover Virtudes
Departamento de Salud Alicante-Sant Joan d'Alacant , Alicante , Spain.
Expert Opin Drug Saf. 2015 Jun;14(6):815-38. doi: 10.1517/14740338.2015.1026326. Epub 2015 Mar 16.
Medication errors have been analyzed as a health professionals' responsibility (due to mistakes in prescription, preparation or dispensing). However, sometimes, patients themselves (or their caregivers) make mistakes in the administration of the medication. The epidemiology of patient medication errors (PEs) has been scarcely reviewed in spite of its impact on people, on therapeutic effectiveness and on incremental cost for the health systems.
This study reviews and describes the methodological approaches and results of published studies on the frequency, causes and consequences of medication errors committed by patients at home. A review of research articles published between 1990 and 2014 was carried out using MEDLINE, Web-of-Knowledge, Scopus, Tripdatabase and Index Medicus.
The frequency of PE was situated between 19 and 59%. The elderly and the preschooler population constituted a higher number of mistakes than others. The most common were: incorrect dosage, forgetting, mixing up medications, failing to recall indications and taking out-of-date or inappropriately stored drugs. The majority of these mistakes have no negative consequences. Health literacy, information and communication and complexity of use of dispensing devices were identified as causes of PEs. Apps and other new technologies offer several opportunities for improving drug safety.
用药错误一直被视为医疗专业人员的责任(归因于处方、调配或发药过程中的失误)。然而,有时患者自身(或其护理人员)在用药时也会犯错。尽管患者用药错误(PEs)对患者、治疗效果以及卫生系统的额外成本有影响,但其流行病学情况却鲜有综述。
本研究回顾并描述了已发表的关于患者在家中用药错误的频率、原因和后果的研究的方法学途径及结果。使用MEDLINE、Web-of-Knowledge、Scopus、Tripdatabase和Index Medicus对1990年至2014年间发表的研究文章进行了综述。
患者用药错误的频率在19%至59%之间。老年人和学龄前儿童群体出现的错误比其他人群更多。最常见的错误包括:剂量不正确、忘记服药、药物混淆、忘记服药指征以及服用过期或储存不当的药物。这些错误大多没有负面后果。健康素养、信息与沟通以及配药装置使用的复杂性被确定为患者用药错误的原因。应用程序和其他新技术为提高用药安全性提供了诸多机会。