Chatzizacharias Nikolaos A, Bradley J Andrew, Harper Simon, Butler Andrew, Jah Asif, Huguet Emmanuel, Praseedom Raaj K, Allison Michael, Gibbs Paul
Nikolaos A Chatzizacharias, J Andrew Bradley, Simon Harper, Andrew Butler, Asif Jah, Emmanuel Huguet, Raaj K Praseedom, Michael Allison, Paul Gibbs, Department of HPB and Transplant Surgery, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom.
World J Gastroenterol. 2015 Mar 14;21(10):3109-13. doi: 10.3748/wjg.v21.i10.3109.
Acute umbilical hernia rupture in patients with hepatic cirrhosis and ascites is an unusual, but potentially life-threatening complication, with postoperative morbidity about 70% and mortality between 60%-80% after supportive care and 6%-20% after urgent surgical repair. Management options include primary surgical repair with or without concomitant portal venous system decompression for the control of the ascites. We present a retrospective analysis of our centre's experience over the last 6 years. Our cohort consisted of 11 consecutive patients (median age: 53 years, range: 36-63 years) with advanced hepatic cirrhosis and refractory ascites. Appropriate patient resuscitation and optimisation with intravenous fluids, prophylactic antibiotics and local measures was instituted. One failed attempt for conservative management was followed by a successful primary repair. In all cases, with one exception, a primary repair with non-absorbable Nylon, interrupted sutures, without mesh, was performed. The perioperative complication rate was 25% and the recurrence rate 8.3%. No mortality was recorded. Median length of hospital stay was 14 d (range: 4-31 d). Based on our experience, the management of ruptured umbilical hernias in patients with advanced hepatic cirrhosis and refractory ascites is feasible without the use of transjugular intrahepatic portosystemic shunt routinely in the preoperative period, provided that meticulous patient optimisation is performed.
肝硬化腹水患者急性脐疝破裂是一种罕见但可能危及生命的并发症,支持治疗后术后发病率约为70%,死亡率在60%-80%之间,紧急手术修复后死亡率在6%-20%之间。治疗选择包括一期手术修复,可伴有或不伴有门静脉系统减压以控制腹水。我们对本中心过去6年的经验进行了回顾性分析。我们的队列包括11例连续的晚期肝硬化和难治性腹水患者(中位年龄:53岁,范围:36-63岁)。采取了适当的患者复苏措施,并通过静脉输液、预防性抗生素和局部措施进行优化。一次保守治疗尝试失败后,进行了一次成功的一期修复。除1例例外,所有病例均采用不可吸收尼龙间断缝合进行一期修复,未使用补片。围手术期并发症发生率为25%,复发率为8.3%。无死亡记录。中位住院时间为14天(范围:4-31天)。根据我们的经验,对于晚期肝硬化和难治性腹水患者的脐疝破裂,只要对患者进行细致的优化,术前不常规使用经颈静脉肝内门体分流术进行治疗是可行的。