Rakici Sema Yilmaz, Erdemli Sema Dogan, Yazici Zihni Acar, Cengiz Ercument, Acar Ozlem Gunay, Tufan Gulnihal
Department of Radiation Oncology, School of Medicine, Recep Tayyip Erdogan University Rize, Turkey.
Department of Radiology, Kanuni Research and Training Hospital Trabzon, Turkey.
Int J Clin Exp Med. 2015 Jan 15;8(1):1453-9. eCollection 2015.
Wernicke's encephalopathy (WE) is a disease classically associated with nutrition deficiency. It is characterized by typical symptoms like confusion, ataxia and ophthalmoparesis, and developes due to thiamine deficieny in alcoholic patients. Recently, it has been shown that WE could ocur in patients with gastric carcinoma without a history of alcohol use. In this paper, we have made some suggestions about early diagnosis, treatment and prevention of WE by discussing the development of WE in a patient with unresectable gastric carcinoma, who had been inpatient for a long time and given radiotherapy and chemotherapy.
韦尼克脑病(WE)是一种典型的与营养缺乏相关的疾病。其特征为诸如意识模糊、共济失调和眼肌麻痹等典型症状,在酒精性患者中因硫胺素缺乏而发病。最近研究表明,无饮酒史的胃癌患者也可能发生韦尼克脑病。本文通过讨论一名长期住院并接受放疗和化疗的不可切除胃癌患者的韦尼克脑病病情发展,对韦尼克脑病的早期诊断、治疗和预防提出了一些建议。