Dantas E O, Aranda C S, Rêgo Silva A M, Tavares F S, Severo Ferreira J F, de Quadros Coelho M A, de Siqueira Kovalhuk L C, Roxo Júnior P, Toledo E C, Porto Neto A C, de Sousa Vieira H M C, Takano O A, Nobre F A, Sano F, Nudelman V, de Farias Sales V S, Silva Segundo G R, Villar Guedes H T, Félix E, Marques S M B, Mazzucchelli J T L, Wandalsen N F, Pinto J A, Paes Barreto I C D, Silva M R, Rullo V E V, Franco J M, Damasceno E, Fahl K, de Moraes-Pinto M I, Del Nero D L, Moraes L S L, Condino-Neto A, Vilela M M, Góes H, Schisler K L, Miranda E, Goudouris E S, Costa Carvalho B T
Federal University of São Paulo, São Paulo, Brazil; Complexo Hospitalar Universitário Professor Edgar Santos - Federal University of Bahia, Salvador, Brazil.
Federal University of São Paulo, São Paulo, Brazil; Complexo Hospitalar Universitário Professor Edgar Santos - Federal University of Bahia, Salvador, Brazil.
Allergol Immunopathol (Madr). 2015 May-Jun;43(3):272-8. doi: 10.1016/j.aller.2014.09.002. Epub 2015 Mar 18.
PIDs are a heterogeneous group of genetic illnesses, and delay in their diagnosis is thought to be caused by a lack of awareness among physicians concerning PIDs. The latter is what we aimed to evaluate in Brazil.
Physicians working at general hospitals all over the country were asked to complete a 14-item questionnaire. One of the questions described 25 clinical situations that could be associated with PIDs and a score was created based on percentages of appropriate answers.
A total of 4026 physicians participated in the study: 1628 paediatricians (40.4%), 1436 clinicians (35.7%), and 962 surgeons (23.9%). About 67% of the physicians had learned about PIDs in medical school or residency training, 84.6% evaluated patients who frequently took antibiotics, but only 40.3% of them participated in the immunological evaluation of these patients. Seventy-seven percent of the participating physicians were not familiar with the warning signs for PIDs. The mean score of correct answers for the 25 clinical situations was 48.08% (±16.06). Only 18.3% of the paediatricians, 7.4% of the clinicians, and 5.8% of the surgeons answered at least 2/3 of these situations appropriately.
There is a lack of medical awareness concerning PIDs, even among paediatricians, who have been targeted with PID educational programmes in recent years in Brazil. An increase in awareness with regard to these disorders within the medical community is an important step towards improving recognition and treatment of PIDs.
原发性免疫缺陷病（PID）是一组异质性的遗传性疾病，其诊断延迟被认为是由于医生对PID缺乏认识所致。我们旨在评估巴西的这种情况。
要求在巴西各地综合医院工作的医生填写一份包含14个条目的问卷。其中一个问题描述了25种可能与PID相关的临床情况，并根据正确答案的百分比给出一个分数。
共有4026名医生参与了这项研究：1628名儿科医生（40.4%）、1436名临床医生（35.7%）和962名外科医生（23.9%）。约67%的医生在医学院或住院医师培训期间了解过PID，84.6%的医生评估过经常使用抗生素的患者，但其中只有40.3%的医生对这些患者进行过免疫学评估。77%的参与医生不熟悉PID的警示信号。对于这25种临床情况，正确答案的平均得分是48.08%（±16.06）。只有18.3%的儿科医生、7.4%的临床医生和5.8%的外科医生对至少三分之二的情况回答正确。
即使在近年来巴西针对其开展了教育项目的儿科医生中，对PID的医学认识也很缺乏。提高医学界对这些疾病的认识是改善PID识别和治疗的重要一步。
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