Tsukioka Takuma, Takahama Makoto, Nakajima Ryu, Kimura Michitaka, Tei Keiko, Yamamoto Ryoji
Department of General Thoracic Surgery, Osaka City General Hospital, 2-13-22 Miyakojima Hondori, Miyakojima-ku, Osaka, 534-0021, Japan,
Gen Thorac Cardiovasc Surg. 2015 Jul;63(7):379-85. doi: 10.1007/s11748-015-0536-9. Epub 2015 Mar 24.
Surgical reconstruction is commonly recommended for the treatment of tuberculous airway stenosis. The clinical conditions underlying tuberculous airway stenosis often involve both cicatricial stenosis and malacia. Surgical reconstruction alone may not improve the respiratory symptoms of patients with both types of airway stenosis. This study retrospectively reviewed patients who underwent surgical reconstruction for tuberculous airway stenosis to investigate the most appropriate treatment for this complicated condition.
Twelve patients with tuberculous airway stenosis underwent surgical reconstruction at our institute from January 2003 to December 2013. The clinical courses of these patients were retrospectively reviewed.
The 12 patients were 2 men and 10 women with a mean age of 36 years (range 17-61 years). The site of stenosis was the left main bronchus in six patients, trachea in four patients, and right main bronchus in two patients. The procedure performed was sleeve lobectomy in five patients, bronchial resection in four patients, and tracheal resection in three patients. Additional airway stenting was performed in two patients with concomitant malacia of the lower trachea. The performance status and Hugh-Jones classification improved postoperatively in all patients. The forced expiratory volume in 1 s as a percent of forced vital capacity and percent of forced expiratory volume in 1 s improved significantly.
Surgical reconstruction is an acceptable treatment for tuberculous airway stenosis. Additional airway stenting may be needed in patients with symptomatic malacia.
手术重建通常被推荐用于治疗结核性气道狭窄。结核性气道狭窄的临床情况通常涉及瘢痕性狭窄和软化。单纯的手术重建可能无法改善同时患有这两种气道狭窄类型患者的呼吸症状。本研究回顾性分析了接受结核性气道狭窄手术重建的患者,以探究针对这种复杂情况的最合适治疗方法。
2003年1月至2013年12月期间,12例结核性气道狭窄患者在我院接受了手术重建。对这些患者的临床病程进行回顾性分析。
12例患者中,男性2例,女性10例,平均年龄36岁(范围17 - 61岁)。狭窄部位为左主支气管6例,气管4例,右主支气管2例。实施的手术为袖状肺叶切除术5例,支气管切除术4例,气管切除术3例。2例合并下气管软化的患者还进行了气道支架置入术。所有患者术后的体能状态和休 - 琼斯分级均有所改善。第1秒用力呼气容积占用力肺活量的百分比以及第1秒用力呼气容积百分比均显著提高。
手术重建是治疗结核性气道狭窄的一种可接受的治疗方法。有症状性软化的患者可能需要额外进行气道支架置入术。