乙二醇中毒后发生致命性中风的罕见病例。
A rare case of fatal stroke after ethylene glycol toxicity.
作者信息
Garg Deepika, Lim Tanna, Irani Mohamad
机构信息
Department of Obstetrics & Gynecology, Maimonides Medical Center, Brooklyn, New York, USA.
Department of Internal Medicine, Atlanta Medical Center, Atlanta, Georgia, USA.
出版信息
BMJ Case Rep. 2015 Mar 25;2015:bcr2014208855. doi: 10.1136/bcr-2014-208855.
A 58-year-old man presented to the emergency department with acute left-sided weakness and left visual field defect. His examination was significant for confusion, acetone odour, tachycardia and tachypnoea. Further blood tests revealed an anion gap of 31 mEq/L, serum osmolal gap of 34 mOsm/kg, and creatinine 3.6 mg/dL. Brain MRI revealed acute infarctions scattered throughout the brain along with generalised oedema. The patient deteriorated rapidly and soon thereafter it was reported that a bottle of antifreeze was found near him at home. Haemodialysis was initiated and the patient received fomepizole and bicarbonate. Three days later the patient did not show any neurological improvement and expired later that day. Ethylene glycol toxicity can rarely present with stroke which can be life-threatening when not diagnosed and managed in a timely fashion.
一名58岁男性因急性左侧肢体无力和左侧视野缺损被送至急诊科。他的检查结果显示意识模糊、有丙酮气味、心动过速和呼吸急促。进一步的血液检查显示阴离子间隙为31 mEq/L，血清渗透压间隙为34 mOsm/kg，肌酐为3.6 mg/dL。脑部磁共振成像显示全脑散在急性梗死灶以及广泛性水肿。患者病情迅速恶化，此后不久据报告在家中他附近发现了一瓶防冻液。开始进行血液透析，患者接受了甲吡唑和碳酸氢盐治疗。三天后患者神经功能未出现任何改善，当天晚些时候死亡。乙二醇中毒很少会表现为中风，若不及时诊断和处理，中风可能会危及生命。
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