人类BK多瘤病毒质粒pBKV(34 - 2)(邓洛普)含有在最初发表的序列中未发现的突变。
Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences.
作者信息
Henriksen Stian, Mittelholzer Christian, Gosert Rainer, Hirsch Hans H, Rinaldo Christine Hanssen
机构信息
Department of Microbiology and Infection Control, University Hospital of North Norway, Tromsø, Norway.
Transplantation and Clinical Virology, Department Biomedicine (Haus Petersplatz), University of Basel, Basel, Switzerland.
出版信息
Genome Announc. 2015 Mar 26;3(2):e00046-15. doi: 10.1128/genomeA.00046-15.
Abstract
The plasmid pBKV (34-2) (ATCC 45025) contains the entire BK polyomavirus Dunlop genome. Sequencing revealed 12 point mutations compared to the GenBank sequence, but only 4 point mutations compared to the published sequence. The origin of these differences is unknown, but may impact virological as well as diagnostic research and development.
摘要
质粒pBKV(34 - 2)(ATCC 45025)包含完整的BK多瘤病毒邓洛普基因组。测序结果显示，与GenBank序列相比有12个点突变，但与已发表序列相比只有4个点突变。这些差异的来源尚不清楚，但可能会影响病毒学以及诊断研究与开发。
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