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一名年轻女性蕈样肉芽肿多种临床和组织病理学特征并存。

Co-existence of various clinical and histopathological features of mycosis fungoides in a young female.

作者信息

Naeini Farahnaz Fatemi, Soghrati Mehrnaz, Abtahi-Naeini Bahareh, Najafian Jamshid, Rajabi Parvin

机构信息

Department of Dermatology, Skin Disease and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Jundishapur University of Medical Sciences, Ahvaz, Iran.

出版信息

Indian J Dermatol. 2015 Mar-Apr;60(2):214. doi: 10.4103/0019-5154.152588.

Abstract

Mycosis fungoides is the most common type of cutaneous T-cell lymphoma (CTCL) and a rare disorder that typically affects older adults with erythematous scaling patches and plaques. Hypopigmented patches are a rare clinical variant of the disease. Granulomatous mycosis fungoides (GMF) is also a rare type of CTCL. No particular clinical criteria are available for the diagnosis of GMF, because of its variable presentations, and so the detection of GMF is primarily considered as a histopathological diagnosis. Rarely, a co-existence of more than one clinical or histopathological feature of mycosis fungoides may be present. To the best of our knowledge this is the first report of MF that shows the simultaneous co-existence of more than one clinical and histopathological variant of MF. We present a 29-year-old female with clinical presentations of both classic and hypopigmented mycosis fungoides (MF), and also the histopathological features of the classic and granulomatous types of the disease.

摘要

蕈样肉芽肿是最常见的皮肤T细胞淋巴瘤(CTCL)类型,是一种罕见疾病,通常影响老年人,表现为红斑鳞屑性斑块。色素减退斑是该疾病的一种罕见临床变异型。肉芽肿性蕈样肉芽肿(GMF)也是一种罕见的CTCL类型。由于GMF表现多样,目前尚无特定的临床诊断标准,因此GMF的诊断主要依靠组织病理学检查。很少会同时出现蕈样肉芽肿的多种临床或组织病理学特征。据我们所知,这是首例显示蕈样肉芽肿同时存在多种临床和组织病理学变异型的报告。我们报告一名29岁女性,其临床表现既有经典型蕈样肉芽肿,又有色素减退型蕈样肉芽肿,组织病理学特征也包括经典型和肉芽肿型。

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