Chatzinasiou Foteini, Papadavid Euaggelia, Korkolopoulou Penelope, Levidou Georgia, Panayiotides Ioannis, Theodoropoulos Konstadinos, Pogka Vasiliki, Asimakopoulos Charalampos, Rigopoulos Dimitrios
2nd Department of Dermatology, Attikon General University Hospital, Athens, Greece.
Department of Pathology, Laikon General Hospital, National and Kapodistrian University, Athens, Greece.
Dermatol Ther. 2015 Sep-Oct;28(5):282-6. doi: 10.1111/dth.12238. Epub 2015 May 14.
Merkel cell carcinoma (MCC) is a rare and highly aggressive neuroendocrine carcinoma of the skin. MCC should be included in the diagnosis of a rapidly growing infiltrating mass and histology as well as laboratory investigations such as Merkel cell polyoma virus (MCPyV) detection are valuable in its diagnosis. We present an unusual case of giant MCC-positive MCPyV in a Greek woman located on the lower leg. Our patient is very unusual in terms of her extensive MCC and her rapid and complete response to radiotherapy.
默克尔细胞癌(MCC)是一种罕见且侵袭性很强的皮肤神经内分泌癌。对于快速生长的浸润性肿块进行诊断时应考虑MCC,组织学检查以及诸如默克尔细胞多瘤病毒(MCPyV)检测等实验室检查对其诊断很有价值。我们报告了一例罕见病例,一名希腊女性小腿部出现巨大的MCC且MCPyV呈阳性。就广泛的MCC以及她对放疗迅速且完全的反应而言,我们的患者非常特殊。