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以单核细胞增生李斯特菌败血症为表现的结肠膀胱瘘

Colovesical fistula presenting as Listeria monocytogenes bacteraemia.

作者信息

Hobbs Mark

机构信息

General Medicine, Middlemore Hospital, Auckland, New Zealand.

出版信息

BMJ Case Rep. 2015 Mar 31;2015:bcr2014209178. doi: 10.1136/bcr-2014-209178.

Abstract

We present a case of colovesical fistula presenting with a clinical syndrome of urosepsis subsequently demonstrated to be due to Listeria monocytogenes bacteraemia. The patient had a history of previous rectal cancer with a low anterior resection and a covering ileostomy that had been reversed 6 months prior to this presentation. L. monocytogenes was also isolated among mixed enteric organisms on urine culture. There were no symptoms or signs of acute gastrointestinal listeriosis or meningoencephalitis. This unusual scenario prompted concern regarding the possibility of communication between bowel and bladder, which was subsequently confirmed with CT and a contrast enema. The patient recovered well with intravenous amoxicillin and to date has declined surgical management of his colovesical fistula. This case illustrates the importance of considering bowel pathology when enteric organisms such as Listeria are isolated from unusual sites.

摘要

我们报告一例结肠膀胱瘘病例,该病例表现为尿脓毒症临床综合征,随后证实是由单核细胞增生李斯特菌血症所致。患者既往有直肠癌病史,曾行低位前切除术并做了回肠造口术,此次发病前6个月回肠造口已还纳。尿液培养中在混合肠道菌群中也分离出了单核细胞增生李斯特菌。患者没有急性胃肠道李斯特菌病或脑膜脑炎的症状或体征。这种不寻常的情况引发了对肠道与膀胱之间存在连通可能性的关注,随后通过CT和结肠造影灌肠得以证实。患者接受静脉注射阿莫西林后恢复良好,迄今为止拒绝了对其结肠膀胱瘘的手术治疗。该病例说明了当从异常部位分离出如李斯特菌等肠道微生物时,考虑肠道病变的重要性。

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本文引用的文献

1
Listeriosis in patients receiving biologic therapies.接受生物疗法治疗的患者李斯特菌病。
Eur J Clin Microbiol Infect Dis. 2013 Sep;32(9):1225-30. doi: 10.1007/s10096-013-1873-1. Epub 2013 Apr 9.
4
The epidemiology of human listeriosis.人类李斯特菌病的流行病学
Microbes Infect. 2007 Aug;9(10):1236-43. doi: 10.1016/j.micinf.2007.05.011. Epub 2007 May 7.
5
Community-acquired Listeria monocytogenes meningitis in adults.成人社区获得性单核细胞增生李斯特菌脑膜炎
Clin Infect Dis. 2006 Nov 15;43(10):1233-8. doi: 10.1086/508462. Epub 2006 Oct 10.
6
Gastroenteritis due to Listeria monocytogenes.由单核细胞增生李斯特菌引起的肠胃炎。
Clin Infect Dis. 2005 May 1;40(9):1327-32. doi: 10.1086/429324. Epub 2005 Mar 31.
7
Practice guidelines for the management of bacterial meningitis.细菌性脑膜炎管理实践指南。
Clin Infect Dis. 2004 Nov 1;39(9):1267-84. doi: 10.1086/425368. Epub 2004 Oct 6.

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