Mrazovac Danijela, Barisić Kutija Marija, Vidas Sania, Kuzman Tomislav, Petricek Igor, Jandroković Sonja, Kalauz Miro, Cerovski Branimir
Coll Antropol. 2014 Dec;38(4):1115-8.
Keratoconus is a progressive, non-inflammatory corneal ectasia characterized by thinning and weakening of the corneal stroma which results in its' protrusion. The onset is during puberty and progresses until the fourth decade of life. In earlier stages, good visual acuity can be provided with spectacles. With progression, contact lenses are considered to be a better therapy. Aim of this study was to determine if there is statistically significant difference between best corrected visual acuity (BCVA) obtained by spectacles and contact lenses in newly diagnosed keratoconus patients, as well as to determine which type of contact lenses provide better BCVA in keratoconus patients. We conducted a 5-year retrospective study of all 2891 patients attending our Contact Lens Department for the first time, searching for patients newly diagnosed with keratoconus. Data were obtained on gender, age, education level, treated eyes, corneal changes, keratoconus severity, BCVA with spectacles, contact lenses and best fitted contact lens type. All patients underwent standard ophthalmic exam, refractometry and keratometry have been done, followed by a spectacles correction and lens fitting. Wilcoxon signed rank test was used for statistical analysis. Results showed that of all 2891 patients examined for the first time, 137 patients (4.74%) have been newly diagnosed with heratoconus, there was male bias (72.26%), mean age 27.7 +/- 9.9 years. Most patients had high school education (51.11%), 3.70% had present corneal changes, 50.37% had mild heratoconus. Majority had keratoconus on both eyes (36.3%) or keratoconus of right eye (26.67%). There was a statistically significant difference (p<0.001) between the BCVA obtained with contact lenses (0.82 +/- 0.21 Snellen chart) rather than spectacles (0.37 +/- 0.27 Snellen chart). The best corrected visual acuity was achieved with rigid gas permeable (RGP) lenses in majority of kera- toconus eyes (51.85%), with semi-gas permeable (SGP) lenses in 43.39%, in 4.23% with polymethyl methacrylate (PMMA) lenses and with hard-soft gas permeable (GP) contact lenses in 0.53% of keratoconus eyes. We have showed that there is a statistically significant difference in BCVA achieved better with contact lenses than with spectacles. RGP lenses are most frequently used in conservative treatment of heratoconus, but SGP lenses were also shown to be a good option that gives equally satisfying final visual acuity with subjective comfortable feeling of contact lens wear.
圆锥角膜是一种进行性、非炎症性角膜扩张,其特征是角膜基质变薄和变弱,导致角膜突出。发病于青春期,持续进展直至生命的第四个十年。在早期阶段,佩戴眼镜可提供良好的视力。随着病情进展,隐形眼镜被认为是更好的治疗方法。本研究的目的是确定新诊断的圆锥角膜患者使用眼镜和隐形眼镜获得的最佳矫正视力(BCVA)之间是否存在统计学上的显著差异,以及确定哪种类型的隐形眼镜能为圆锥角膜患者提供更好的BCVA。我们对首次到我们隐形眼镜科就诊的所有2891例患者进行了一项为期5年的回顾性研究,寻找新诊断为圆锥角膜的患者。获取了有关性别、年龄、教育水平、患眼、角膜变化、圆锥角膜严重程度、戴眼镜时的BCVA、隐形眼镜以及最合适的隐形眼镜类型的数据。所有患者均接受了标准眼科检查、验光和角膜曲率测量,随后进行眼镜矫正和镜片适配。采用Wilcoxon符号秩检验进行统计分析。结果显示,在首次接受检查的所有2891例患者中,137例(4.74%)新诊断为圆锥角膜,存在男性偏倚(72.26%),平均年龄27.7±9.9岁。大多数患者接受过高中教育(51.11%),3.70%有当前角膜变化,50.37%为轻度圆锥角膜。大多数患者双眼患有圆锥角膜(36.3%)或右眼患有圆锥角膜(26.67%)。使用隐形眼镜获得的BCVA(Snellen视力表0.82±0.21)与使用眼镜获得的BCVA(Snellen视力表0.37±0.27)之间存在统计学上的显著差异(p<0.001)。在大多数圆锥角膜患眼中(51.85%),使用硬性透气性(RGP)镜片可实现最佳矫正视力,43.39%使用半透气性(SGP)镜片,4.23%使用聚甲基丙烯酸甲酯(PMMA)镜片,0.53%的圆锥角膜患眼使用硬软透气性(GP)隐形眼镜。我们已经表明,使用隐形眼镜获得的BCVA比使用眼镜获得的BCVA有统计学上的显著差异。RGP镜片在圆锥角膜的保守治疗中最常使用,但SGP镜片也被证明是一个很好的选择,能提供同样令人满意的最终视力,且佩戴隐形眼镜时有主观舒适感。