Mota Paula, de Belder Adam, Leitão-Marques António
Cardiovascular Intervention Unit, Coimbra University Hospital Centre, Coimbra, Portugal.
Sussex Cardiac Centre, Brighton and Sussex University Hospitals, Brighton, East Sussex, United Kingdom.
Rev Port Cardiol. 2015 Apr;34(4):271-8. doi: 10.1016/j.repc.2014.11.011. Epub 2015 Apr 3.
Percutaneous coronary intervention is currently the most common form of revascularization for symptomatic coronary artery disease. In elderly, diabetic and renal patients, there is an increased prevalence of calcified coronary disease. Rotational atherectomy (RA) can be useful in the treatment of these lesions. Plaque removal was initially proposed as an alternative to balloon angioplasty, hence RA required high-velocity protocols with large-sized burrs (over 2.0 mm). With a high incidence of acute complications and disappointing restenosis rates, the use of RA dwindled. However, the advent of drug-eluting stents, which significantly decreased the rate of restenosis, led to the repositioning of RA as an adjunctive technique in the preparation of densely calcified lesions, improving stent delivery and expansion. In recent years, a better understanding of the mechanism of action of RA has changed it from a plaque debulking to a compliance modifying technique. As a result, RA has become less aggressive, using smaller size burrs and lower rotational speeds. This conservative approach has improved immediate results, with increased safety and better long-term outcomes. In this review paper, the technique of RA is explained in the light of current knowledge.
经皮冠状动脉介入治疗是目前有症状冠状动脉疾病最常见的血运重建方式。在老年、糖尿病和肾病患者中,冠状动脉钙化疾病的患病率增加。旋磨术(RA)在这些病变的治疗中可能有用。斑块切除术最初被提议作为球囊血管成形术的替代方法,因此RA需要使用大尺寸磨头(超过2.0毫米)的高速方案。由于急性并发症发生率高且再狭窄率令人失望,RA的使用逐渐减少。然而,药物洗脱支架的出现显著降低了再狭窄率,使得RA重新定位为一种辅助技术,用于准备严重钙化病变,改善支架输送和扩张。近年来,对RA作用机制的更好理解使其从一种斑块减容技术转变为一种顺应性改善技术。结果,RA变得不那么激进,使用更小尺寸的磨头和更低的旋转速度。这种保守方法改善了即刻效果,提高了安全性并带来了更好的长期结果。在这篇综述文章中,根据当前知识对RA技术进行了解释。