Kim Shin Hyung, Sun Jong Min, Yoon Kyung Bong, Moon Joo Hwa, An Jong Rin, Yoon Duck Mi
Department of Anesthesiology and Pain Medicine, Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Korean J Pain. 2015 Apr;28(2):137-43. doi: 10.3344/kjp.2015.28.2.137. Epub 2015 Apr 1.
Insomnia is becoming increasingly recognized as a clinically important symptom in patients with chronic low back pain (CLBP). In this retrospective study, we have determined risk factors associated with clinical insomnia in CLBP patients in a university hospital in Korea.
Data from four-hundred and eighty one CLBP patients was analyzed in this study. The Insomnia Severity Index (ISI) was used to determine the presence of clinical insomnia (ISI score ≥ 15). Patients' demographics and pain-related factors were evaluated by logistic regression analysis to identify risk factors of clinical insomnia in CLBP.
It was found that 43% of patients reported mild to severe insomnia after the development of back pain. In addition, 20% of patients met the criteria for clinically significant insomnia (ISI score ≥ 15). In a stepwise multivariate analysis, high pain intensity, the presence of comorbid musculoskeletal pain and neuropathic pain components, and high level of depression were strongly associated with clinical insomnia in CLBP. Among these factors, the presence of comorbid musculoskeletal pain other than back pain was the strongest determinant, with the highest odds ratio of 8.074 (95% CI 4.250 to 15.339) for predicting clinical insomnia.
Insomnia should be addressed as an integral part of pain management in CLBP patients with these risk factors, especially in patients suffering from CLBP with comorbid musculoskeletal pain.
失眠日益被认为是慢性下腰痛(CLBP)患者临床上的重要症状。在这项回顾性研究中,我们确定了韩国一家大学医院中与CLBP患者临床失眠相关的危险因素。
本研究分析了481例CLBP患者的数据。采用失眠严重程度指数(ISI)来确定临床失眠的存在(ISI评分≥15)。通过逻辑回归分析评估患者的人口统计学和疼痛相关因素,以确定CLBP患者临床失眠的危险因素。
发现43%的患者在出现背痛后报告有轻度至重度失眠。此外,20%的患者符合临床上显著失眠的标准(ISI评分≥15)。在逐步多变量分析中,高疼痛强度、合并肌肉骨骼疼痛和神经性疼痛成分以及高水平的抑郁与CLBP患者的临床失眠密切相关。在这些因素中,除背痛外合并肌肉骨骼疼痛是最强的决定因素,预测临床失眠的最高优势比为8.074(95%CI 4.250至15.339)。
对于有这些危险因素的CLBP患者,尤其是患有合并肌肉骨骼疼痛的CLBP患者,应将失眠作为疼痛管理的一个组成部分加以解决。