Rogers Richard G, Boardman Jason D, Pendergast Philip M, Lawrence Elizabeth M
Department of Sociology and Population Program, Institute of Behavioral Science, 483 UCB, University of Colorado, Boulder, CO 80309-0483, United States.
Department of Sociology and Population Program, Institute of Behavioral Science, 483 UCB, University of Colorado, Boulder, CO 80309-0483, United States.
Drug Alcohol Depend. 2015 Jun 1;151:38-46. doi: 10.1016/j.drugalcdep.2015.02.039. Epub 2015 Mar 26.
We examine the links between 41 problems related to alcohol consumption and the risk of death among adults in the United States.
We use Cox proportional hazards models and data from the nationally representative prospective National Health Interview Survey-Linked Mortality Files (NHIS-LMF).
Drinking problems are relatively common among moderate and heavy drinkers and these problems are associated with increases in the risk of death. The strongest associations between problem drinking and mortality involved cases in which physicians, family members, or friends intervened to suggest reduced drinking. Losing one's job because of drinking problems within their lifetime (HR = 1.36, 95% confidence interval [CI]: 1.11, 1.65) was strongly linked to mortality risk. Social risks were equally or more strongly linked to mortality than physiological consequences of alcohol abuse such as lifetime reports of needing a drink to stop shaking or getting sick (HR = 1.23, 95% CI: 1.09, 1.40). Most importantly, these associations were evident despite statistical controls for alcohol consumption levels and demographic, social, economic, behavioral, health, and geographic factors.
Our results highlight the independent and additive effects of alcohol-related problems and alcohol consumption levels on the risk of death. We recommend that studies examining the mortality risks of alcohol consumption take into account drinking status and also specific drinking-related problems, paying particular attention to social problems related to alcohol use or abuse.
我们研究了与饮酒相关的41个问题与美国成年人死亡风险之间的联系。
我们使用Cox比例风险模型以及来自具有全国代表性的前瞻性国民健康访谈调查关联死亡率文件(NHIS-LMF)的数据。
饮酒问题在中度和重度饮酒者中相对普遍,并且这些问题与死亡风险增加有关。问题饮酒与死亡率之间最强的关联涉及医生、家庭成员或朋友进行干预以建议减少饮酒的情况。因饮酒问题在一生中失去工作(风险比[HR]=1.36,95%置信区间[CI]:1.11,1.65)与死亡风险密切相关。社会风险与死亡率的关联与酒精滥用的生理后果(如一生中报告需要饮酒来停止颤抖或生病)相同或更强(HR=1.23,95%CI:1.09,1.40)。最重要的是,尽管对饮酒水平以及人口统计学、社会、经济、行为、健康和地理因素进行了统计控制,但这些关联仍然明显。
我们的结果强调了与酒精相关的问题和饮酒水平对死亡风险的独立和累加效应。我们建议,研究饮酒的死亡风险时应考虑饮酒状况以及具体的与饮酒相关的问题,尤其要关注与酒精使用或滥用相关的社会问题。