谁决定了乙肝病毒暴露的结局？
Who determines the outcomes of HBV exposure?
机构信息
Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310003, China.
出版信息
Trends Microbiol. 2015 Jun;23(6):328-9. doi: 10.1016/j.tim.2015.04.001. Epub 2015 Apr 9.
Until recently, the reason for age-dependent immune clearance of hepatitis B virus remained elusive. A new study has revealed that establishment of the commensal gut microbiota could modulate the liver immunity phenotype in a hydrodynamic transfection mouse model, suggesting that natural gut-liver interactions can help achieve rapid viral clearance.
直到最近，年龄相关的乙型肝炎病毒免疫清除的原因仍难以捉摸。一项新的研究表明，定植的共生肠道微生物群可以在流体动力学转染小鼠模型中调节肝脏免疫表型，这表明天然的肠道-肝脏相互作用可以帮助实现快速的病毒清除。
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