Isoda Susumu, Imoto Kiyotaka, Uchida Keiji, Nishimura Kenji, Karube Norihisa, Suzuki Shinichi, Masuda Munetaka
Department of Cardiovascular Surgery, Yokohama City University Medical Center, Yokohama, Japan.
Department of Cardiovascular Surgery, National Defense Medical College, Tokorozawa, Japan.
J Card Surg. 2015 Jun;30(6):488-93. doi: 10.1111/jocs.12546. Epub 2015 Apr 15.
Residual shunting and mortality are problems associated with the current surgical repair techniques for postinfarction ventricular septal defects (VSD). We developed the "sandwich technique" via a right ventricle incision and assessed the surgical outcome of 13 years of experience with this technique.
Between June 2001 and March 2013, 25 consecutive patients with postinfarction VSD underwent surgical repair using this technique. This technique includes the following: Application of direct ultrasonography to the right ventricular (RV) wall enables the surgeon to visualize the lesion, perform an appropriate incision into the RV, and perform a trabecular resection. One patch is placed on the left ventricular (LV) side and the other on the RV side of the VSD. The VSD is sealed with gelatin-resorcin-formalin (GRF) glue between the two patches.
Thirty-day mortality was 0% (0/25 case). A postoperative major shunt occurred in three patients (12%, 3/25) and two of them required reoperation (8%, 2/25). Hospital mortality was 28% (seven patients). Mean follow-up period was 4.2 ± 3.7 years. The overall survival at one, five, and 10 years was 71 ± 9%, 65 ± 10%, and 56 ± 12%, respectively. There was no cardiac death during follow-up in the patients who survived for six months after the surgery. No tissue degeneration related to GRF glue was noted.
The "sandwich technique" via a right ventricle incision results in a low incidence of postoperative leak and good short- and mid-term survival.
残余分流和死亡率是目前心肌梗死后室间隔缺损(VSD)手术修复技术所面临的问题。我们通过右心室切口开发了“三明治技术”,并评估了13年使用该技术的手术结果。
2001年6月至2013年3月期间,25例连续的心肌梗死后VSD患者接受了使用该技术的手术修复。该技术包括以下步骤:对右心室(RV)壁进行直接超声检查,使外科医生能够可视化病变,在RV上进行适当的切口,并进行小梁切除术。一块补片放置在室间隔缺损的左心室(LV)侧,另一块放置在RV侧。在两块补片之间用明胶-间苯二酚-甲醛(GRF)胶水封闭室间隔缺损。
30天死亡率为0%(0/25例)。3例患者(12%,3/25)术后出现主要分流,其中2例需要再次手术(8%,2/25)。住院死亡率为28%(7例患者)。平均随访期为4.2±3.7年。1年、5年和10年的总生存率分别为71±9%、65±10%和56±12%。术后存活6个月的患者在随访期间无心脏死亡。未发现与GRF胶水相关的组织退变。
通过右心室切口的“三明治技术”导致术后渗漏发生率低,短期和中期生存率良好。